Proctolin

Base Information

Chemical Name:Proctolin
CAS No.:57966-42-4
Molecular Formula:C₃₀H₄₈N₈O₈
Molecular Weight:648.76
Hs Code.:
DSSTox Substance ID:DTXSID80956793
Nikkaji Number:J11.208I
Wikipedia:Proctolin
ChEMBL ID:CHEMBL295536
Mol file:57966-42-4.mol

Synonyms:Arg-Tyr-Leu-Pro-Thr;arginyl-tyrosyl-leucyl-prolyl-threonyl;Gut Factor;proctolin

Suppliers and Price of Proctolin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Proctolin
2.5mg
$ 140.00

American Custom Chemicals Corporation
PROCTOLIN 95.00%
1MG
$ 589.16

Alfa Aesar
Proctolin
1mg
$ 60.70

Total 11 raw suppliers

Chemical Property of Proctolin

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:3.28±0.10(Predicted)
Flash Point:°C
PSA：283.76000
Density:1.43g/cm³
LogP:2.83220
Water Solubility.:Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
XLogP3:-4.5
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:17
Exact Mass:648.35951052
Heavy Atom Count:46
Complexity:1080

Purity/Quality:

97% ^*data from raw suppliers

Proctolin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CCCN=C(N)N)N
Isomeric SMILES:C[C@H]([C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CCCN=C(N)N)N)O

Technology Process of Proctolin

There total 8 articles about Proctolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

: 1096160-70-1
Z-Arg(Z₂)-Tyr-Leu-Pro-Thr-OBn

: 72273-85-9,72273-86-0,72273-87-1,72273-88-2,72282-50-9,57966-42-4
Arg-Tyr-Leu-Pro-Thr

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 6h;
DOI:10.1016/j.jfluchem.2007.12.005

Reference yield:

: 3392-09-4
Boc-Leu-ONSu

: 72273-85-9,72273-86-0,72273-87-1,72273-88-2,72282-50-9,57966-42-4
Arg-Tyr-Leu-Pro-Thr

Guidance literature:: Multi-step reaction with 6 steps

1: 2.) DCC, N-hydroxysuccinimide (HO-Su)

2: CF₃COOH / CH₂Cl₂

3: DCC, N-hydroxysuccinimide (HO-Su)

4: CF₃COOF / CH₂Cl₂

5: DCC, N-hydroxysuccinimide (HO-Su)

6: CH₃SO₃H / various solvent(s)

With 1-hydroxy-pyrrolidine-2,5-dione; methanesulfonic acid; tetrafluoroacetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane;

Reference yield:

: 2130-96-3,54784-43-9
O-benzyl-N-tert-butoxycarbonyl-L-tyrosine

: 72273-85-9,72273-86-0,72273-87-1,72273-88-2,72282-50-9,57966-42-4
Arg-Tyr-Leu-Pro-Thr

Guidance literature:: Multi-step reaction with 4 steps

1: DCC, N-hydroxysuccinimide (HO-Su)

2: CF₃COOF / CH₂Cl₂

3: DCC, N-hydroxysuccinimide (HO-Su)

4: CH₃SO₃H / various solvent(s)

With 1-hydroxy-pyrrolidine-2,5-dione; methanesulfonic acid; tetrafluoroacetic acid; dicyclohexyl-carbodiimide; In dichloromethane;