(4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate

Base Information

• Chemical Name: (4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate
• CAS No.: 1204518-02-4
• Molecular Formula: C17H18F3IO3S
• Molecular Weight: 486.294
• Hs Code.: 2902909090
• Mol file: 1204518-02-4.mol

Synonyms:(4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate;(4-Methylphenyl)(2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate;Mesityl(p-tolyl)iodonium triflate

Chemical Property of (4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate

Chemical Property:

• Melting Point: 177.0 to 182.0 °C
• PSA: 65.58000
• LogP: 2.18080
• Solubility.: soluble in Methanol

Purity/Quality:

97% ^*data from raw suppliers

(4-Methylphenyl)(2,4,6-trimethylphenyl)iodonium triflate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 20040208
• Hazard Codes: T
• Statements: 25-36/37/38
• Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (4-Methylphenyl)(2,4,6-trimethylphenyl)iodonium Triflate is a reagent used in organic synhesis, normally applied in arylation reactions and in iodonium metathesis reactions.

Technology Process of (4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate

There total 4 articles about (4-Methylphenyl)(2,4,6-triMethylphenyl)iodoniuM triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

trifluorormethanesulfonic acid (1493-13-6) + 4-tolyl iodide (624-31-7) + 1,3,5-trimethyl-benzene (108-67-8) → 4-methylphenyl(2,4,6-trimethylphenyl)iodonium triflate (1204518-02-4)

Guidance literature:

In acetonitrile; Electrochemical reaction; Green chemistry;

DOI:10.1039/d1ob00457c

Reference yield: 90.0%

trifluorormethanesulfonic acid (1493-13-6) + 2-(diacetoxyiodo)mesitylene (33035-41-5) + toluene (108-88-3,15644-74-3,16713-13-6) → 4-methylphenyl(2,4,6-trimethylphenyl)iodonium triflate (1204518-02-4)

Guidance literature:

In acetonitrile; at 20 ℃; for 3h;

DOI:10.1007/s11172-020-3035-9

Reference yield: 82.0%

trifluorormethanesulfonic acid (1493-13-6) + iodomesitylene diacetate + toluene (108-88-3,15644-74-3,16713-13-6) → 4-methylphenyl(2,4,6-trimethylphenyl)iodonium triflate (1204518-02-4)

Guidance literature:

In acetonitrile; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2019.05.033

upstream raw materials:

trifluorormethanesulfonic acid

4-tolyl iodide

1,3,5-trimethyl-benzene

trimethylsilyl trifluoromethanesulfonate

Downstream raw materials:

11-[1-p-tolylbut-(Z)-ylidene]-6,11-dihydroindolo[1,2-b]isoquinoline

N-butyl-N-(p-tolyl)acetamide

4-methylphenyl 4’-methoxyphenyl selenide

1-phenyl-2-p-tolylethanone

Refernces

• 1、 Elsherbini, Mohamed,Moran, Wesley J.. "Scalable electrochemical synthesis of diaryliodonium salts". supporting information. p. 4706 - 4711. Retrieved 2021/06/11.
• 2、 Bouquin, Maxime,Jaroschik, Florian,Taillefer, Marc. "Versatile and base-free copper-catalyzed α-arylations of aromatic ketones using diaryliodonium salts". supporting information. . Retrieved 2021/06/11.