1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate

Base Information

Chemical Name:1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate
CAS No.:122019-53-8
Molecular Formula:C₁₂H₁₉NO₅
Molecular Weight:257.287
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90445800
Nikkaji Number:J1.029.942J
Mol file:122019-53-8.mol

Synonyms:122019-53-8;1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate;Methyl 1-Boc-3-oxopiperidine-2-carboxylate;1-O-tert-butyl 2-O-methyl 3-oxopiperidine-1,2-dicarboxylate;MFCD15071869;SCHEMBL4147539;DTXSID90445800;BEKOYYXLZWEFQT-UHFFFAOYSA-N;AC1246;AKOS015897809;SB43890;CS-11731;SY028923;Methyl1-Boc-3-oxopiperidine-2-carboxylate;CS-0442920;FT-0769316;2-Methyl 1-boc-3-oxopiperidine-2-carboxylate;A891240;1-(Tert-butyl) 2-methyl 3-oxopiperidine-1,2-dicarboxylate;1-(1,1-dimethylethyl) 2-methyl 3-oxo-1,2-piperidinedicarboxylate;1-(tert-Butyloxycarbonyl)-3-oxo-2-piperidinecarboxylic acid methyl ester

Suppliers and Price of 1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 1-Boc-3-oxopiperidine-2-carboxylate
1 g
$ 1904.00

SynQuest Laboratories
Methyl 1-Boc-3-oxopiperidine-2-carboxylate
250 mg
$ 784.00

Crysdot
1-tert-Butyl2-methyl3-oxopiperidine-1,2-dicarboxylate 95+%
1g
$ 653.00

Chemenu
1-tert-Butyl2-methyl3-oxopiperidine-1,2-dicarboxylate 95%
1g
$ 617.00

American Custom Chemicals Corporation
1-TERT-BUTYL-2-METHYL 3-OXOPIPERIDINE-1,2-DICARBOXYLATE 95.00%
5MG
$ 497.63

Alichem
1-tert-Butyl2-methyl3-oxopiperidine-1,2-dicarboxylate
1g
$ 653.12

AK Scientific
1-tert-Butyl2-methyl3-oxopiperidine-1,2-dicarboxylate
1g
$ 880.00

Total 10 raw suppliers

Chemical Property of 1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate

Chemical Property:

PSA：72.91000
LogP:1.06590
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:257.12632271
Heavy Atom Count:18
Complexity:358

Purity/Quality:

97% ^*data from raw suppliers

Methyl 1-Boc-3-oxopiperidine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC(=O)C1C(=O)OC

Technology Process of 1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate

There total 9 articles about 1-tert-Butyl 2-methyl 3-oxopiperidine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: cis-3-hydroxy-1,2-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester

: 122019-53-8
3-oxo-1,2-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; for 0.25h;
DOI:10.1021/jm00129a016

Reference yield: 53.0%

: 62733-99-7
methyl 3-hydroxypicolinate

: 24424-99-5
di-tert-butyl dicarbonate

: 122019-53-8
3-oxo-1,2-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester

Guidance literature:: methyl 3-hydroxypicolinate; With platinum(IV) oxide; hydrogen; In methanol; at 10 - 30 ℃; for 20h; under 760.051 Torr;

di-tert-butyl dicarbonate; With sodium hydrogencarbonate; at 10 - 30 ℃; for 2h; pH=10;