N,N-Di-Boc-2-iodoaniline

Base Information

Chemical Name:N,N-Di-Boc-2-iodoaniline
CAS No.:870703-53-0
Molecular Formula:C₁₆H₂₂INO₄
Molecular Weight:419.259
Hs Code.:
European Community (EC) Number:635-923-3
DSSTox Substance ID:DTXSID90584566
Wikidata:Q82476246
Mol file:870703-53-0.mol

Synonyms:N,N-Di-Boc-2-iodoaniline;870703-53-0;tert-butyl N-(2-iodophenyl)-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate;Di-tert-butyl (2-iodophenyl)iminodicarbonate;SCHEMBL17183930;DTXSID90584566;N,N-Di-Boc-2-iodoaniline, 97%;Di-tert-butyl (2-iodophenyl)-2-imidodicarbonate

Suppliers and Price of N,N-Di-Boc-2-iodoaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N,N-Di-Boc-2-iodoaniline 97%
10g
$ 158.00

American Custom Chemicals Corporation
N,N-DI-BOC-2-IODOANILINE 95.00%
10G
$ 1240.04

AK Scientific
N,N-Di-Boc-2-iodoaniline
10g
$ 258.00

Total 7 raw suppliers

Chemical Property of N,N-Di-Boc-2-iodoaniline

Chemical Property:

Vapor Pressure:9.94E-07mmHg at 25°C
Melting Point:109-113 °C(lit.)
Boiling Point:403.8°C at 760 mmHg
PKA:-1.46±0.50(Predicted)
Flash Point:198°C
PSA：55.84000
Density:1.452g/cm³
LogP:4.96780
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:419.05936
Heavy Atom Count:22
Complexity:383

Purity/Quality:

99% ^*data from raw suppliers

N,N-Di-Boc-2-iodoaniline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(C1=CC=CC=C1I)C(=O)OC(C)(C)C

Technology Process of N,N-Di-Boc-2-iodoaniline

There total 3 articles about N,N-Di-Boc-2-iodoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 161117-84-6
tert-butyl 2-iodophenylcarbamate

: 870703-53-0
N-di(tert-butylcarboxy)aniline

Guidance literature:: tert-butyl 2-iodophenylcarbamate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

di-tert-butyl dicarbonate; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 17h; Inert atmosphere;
DOI:10.1002/chem.201002287

Reference yield: 81.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 615-43-0
2-iodophenylamine

: 870703-53-0
N-di(tert-butylcarboxy)aniline

: 161117-84-6
tert-butyl 2-iodophenylcarbamate

Guidance literature:: 2-iodophenylamine; With sodium hexamethyldisilazane; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃; for 1.5h; Inert atmosphere;
DOI:10.1002/anie.201905814