Uldazepam

Base Information

• Chemical Name: Uldazepam
• CAS No.: 28546-58-9
• Molecular Formula: C18H15 Cl2 N3 O
• Molecular Weight: 360.242
• Hs Code.: 2933990090
• UNII: VAE9C0350C
• DSSTox Substance ID: DTXSID70182766
• Nikkaji Number: J20.172C
• Wikipedia: Uldazepam
• Wikidata: Q7878818
• NCI Thesaurus Code: C98142
• ChEMBL ID: CHEMBL2105584
• Mol file: 28546-58-9.mol

Synonyms:U 31,920;U 31920;U-31,920;U-31920;uldazepam

Chemical Property of Uldazepam

Chemical Property:

• Vapor Pressure: 2.01E-09mmHg at 25°C
• Boiling Point: 481.3°C at 760 mmHg
• PKA: 2.36±0.20(Predicted)
• Flash Point: 244.9°C
• PSA: 45.98000
• Density: 1.3g/cm³
• LogP: 3.84370
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 359.0592175
• Heavy Atom Count: 24
• Complexity: 509

Purity/Quality:

97% ^*data from raw suppliers

Uldazepam ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCONC1=NC2=C(C=C(C=C2)Cl)C(=NC1)C3=CC=CC=C3Cl
• Uses: Sedative-hypnotic. Uldazepam, can be used as tranquilizer, in treating patients with anxiety syndromes.

Technology Process of Uldazepam

There total 1 articles about Uldazepam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Uldazepam (28546-58-9)

Guidance literature:

Thioketon IIIb, Allyloxyamin*HCl, Δ;

DOI:10.1002/jlcr.2580120419

Reference yield: 66.0%

Uldazepam (28546-58-9) → 2-amino-7-chloro-5-(2-chlorophenyl)-3H-1,4-benzodiazepine (35670-34-9)

Guidance literature:

With hydrogen; Raney-Ni (2percent Pd); In ethanol; for 4h; Ambient temperature;

DOI:10.1002/ardp.19883210205

Reference yield:

Uldazepam (28546-58-9) → N-[7-Chloro-5-(2-chloro-phenyl)-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-yl]-O-propyl-hydroxylamine + O-Allyl-N-[7-chloro-5-(2-chloro-phenyl)-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-yl]-hydroxylamine

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; for 2h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1002/ardp.19883210205

Downstream raw materials:

6-Chlor-4-(o-chlorphenyl)-2-methyl-3,4-dihydrochinazolin

2-amino-7-chloro-5-(2-chlorophenyl)-3H-1,4-benzodiazepine