4-Pregnene-20,21-diol-3,11-dione, (20R)-

Base Information

• Chemical Name: 4-Pregnene-20,21-diol-3,11-dione, (20R)-
• CAS No.: 600-69-1
• Molecular Formula: C₂₁H₃₀O₄
• Molecular Weight: 346.467
• UNII: 7J3A0YK2NA
• Nikkaji Number: J6.801B
• Wikidata: Q27268380
• Mol file: 600-69-1.mol

Synonyms:UNII-7J3A0YK2NA;7J3A0YK2NA;4-Pregnene-20,21-diol-3,11-dione, (20R)-;600-69-1;Pregn-4-ene-3,11-dione, 20,21-dihydroxy-, (20R)-;Pregn-4-ene-3,11-dione, 20alpha,21-dihydroxy-;(20R)-4-pregnene-20,21-diol-3,11-dione;Q27268380;PREGN-4-ENE-3,11-DIONE, 20.ALPHA.,21-DIHYDROXY-

Chemical Property of 4-Pregnene-20,21-diol-3,11-dione, (20R)-

Chemical Property:

• PSA: 74.60000
• LogP: 2.66670
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 346.21440943
• Heavy Atom Count: 25
• Complexity: 638

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4C(CO)O)C
• Isomeric SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4[C@H](CO)O)C

Technology Process of 4-Pregnene-20,21-diol-3,11-dione, (20R)-

There total 3 articles about 4-Pregnene-20,21-diol-3,11-dione, (20R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 20β-21-Dihydroxypregn-4-en-3,11-dion (116-56-3,600-69-1,600-70-4)

Guidance literature:

11b und CH3COOH;

DOI:10.1021/jo00973a034

Reference yield:

11-dehydrocorticosterone (72-23-1) → (20R)-20.21-dihydroxy-pregnene-(4)-dione-(3.11) (600-69-1)

Guidance literature:

With rabbit 3-hydroxyhexobarbital dehydrogenase (AKR₁C₂₉); NADPH; In aq. phosphate buffer; ethyl acetate; at 37 ℃; for 0.5h; pH=7.4; Catalytic behavior; Kinetics; Enzymatic reaction;

DOI:10.1016/j.bcp.2013.08.024

Reference yield:

20αF.21-diacetoxy-5β-pregnanedione-(3.11) → (20R)-20.21-dihydroxy-pregnene-(4)-dione-(3.11) (600-69-1)

Guidance literature:

With bromine; acetic acid; Erhitzen des Reaktionsprodukts mit Pyridin und Behandeln des danach erhaltenen Reaktionsprodukts mit K₂CO₃ und KHCO₃ in wss.Methanol;

DOI:10.1021/ja01216a010

upstream raw materials:

11-dehydrocorticosterone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 600-69-1 20β,21-Dihydroxypregna-4-ene-3,11-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send