19-Norepiandrosterone

Base Information

• Chemical Name: 19-Norepiandrosterone
• CAS No.: 10002-93-4
• Molecular Formula: C18H28O2
• Molecular Weight: 276.419
• UNII: XRW43NN001
• DSSTox Substance ID: DTXSID101017045
• Nikkaji Number: J505.851A
• Wikidata: Q27293974
• Mol file: 10002-93-4.mol

Synonyms:19-norepiandrosterone;10002-93-4;XRW43NN001;UNII-XRW43NN001;5alpha-Estran-17-one, 3beta-hydroxy-;(3beta,5alpha)-3-Hydroxyestran-17-one;Estran-17-one, 3-hydroxy-, (3beta,5alpha)-;(3S,5S,8R,9R,10S,13S,14S)-3-hydroxy-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-one;SCHEMBL9417481;DTXSID101017045;5.ALPHA.-ESTRAN-17-ONE, 3.BETA.-HYDROXY-;(3.BETA.,5.ALPHA.)-3-HYDROXYESTRAN-17-ONE;Q27293974;ESTRAN-17-ONE, 3-HYDROXY-, (3.BETA.,5.ALPHA.)-

Chemical Property of 19-Norepiandrosterone

Chemical Property:

• PSA: 37.30000
• LogP: 3.56900
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 276.208930132
• Heavy Atom Count: 20
• Complexity: 418

Purity/Quality:

98%min ^*data from raw suppliers

5-ALPHA-ESTRAN-3-BETA-OL-17-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C4CCC(CC4CCC3C1CCC2=O)O
• Isomeric SMILES: C[C@]12CC[C@@H]3[C@H]4CC[C@@H](C[C@@H]4CC[C@H]3[C@@H]1CCC2=O)O
• Uses: 19-Norepiandrosterone is an metabolite of Nandrolone (N315000), an androgenic anabolic steroid illegally used as a growth-promoting agent in animal breeding and as a performance enhancer in athletics

Technology Process of 19-Norepiandrosterone

There total 11 articles about 19-Norepiandrosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

17β-hydroxy-5α-estran-3-one (1434-85-1) → 5α‐estrane‐3α,17β‐diol (10002-95-6) + 5α‐estrane‐3β,17β‐diol (1816-75-7) + 19-Norandrosterone (1225-01-0) + 19-nor-5α-androstan-3β-ol-17-one (10002-93-4)

Guidance literature:

for 336h; Further byproducts given; Rhodotorula mucilaginosa;

Reference yield: 15.0%

17β-hydroxy-5α-estran-3-one (1434-85-1) → 5α‐estrane‐3α,17β‐diol (10002-95-6) + 19-Norandrosterone (1225-01-0) + 5α-estrane-3,17-dione (5696-58-2) + 19-nor-5α-androstan-3β-ol-17-one (10002-93-4)

Guidance literature:

for 336h; Further byproducts given; Rhodotorula mucilaginosa;

Reference yield:

→ 3β-Hydroxy-19-nor-5α-androstanon-(17) (1225-01-0,10002-93-4,22834-69-1,33036-33-8,64044-10-6,65556-19-6,76156-26-8,94424-27-8,95340-46-8,130930-11-9)

Guidance literature:

3β,17β-Dihydroxy-19-nor-5α-androstan, Digitonin/A., dann CrO3/HOAc; Py.;

DOI:10.1021/ja01490a062

upstream raw materials:

17β-hydroxy-5α-estran-3-one

Refernces