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STK393606

Base Information Edit
STK393606

Synonyms:STK393606

Suppliers and Price of STK393606
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Chemenu
  • 2-(((6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio)methyl)benzonitrile 97%
  • 1g
  • $ 1290.00
  • Cayman Chemical
  • STK393606 ≥98%
  • 25mg
  • $ 852.00
  • Cayman Chemical
  • STK393606 ≥98%
  • 1mg
  • $ 50.00
  • Cayman Chemical
  • STK393606 ≥98%
  • 10mg
  • $ 366.00
  • Cayman Chemical
  • STK393606 ≥98%
  • 5mg
  • $ 195.00
  • ApexBio Technology
  • STK393606
  • 1mg
  • $ 62.00
  • American Custom Chemicals Corporation
  • 2-[(6-BROMO-3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)SULFANYLMETHYL]BENZONITRILE 95.00%
  • 5MG
  • $ 497.63
  • AK Scientific
  • 2-[[(6-Bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile
  • 25mg
  • $ 1163.00
  • AK Scientific
  • 2-[[(6-Bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile
  • 10mg
  • $ 556.00
  • A1 Biochem Labs
  • 2-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-ylsulfanylmethyl)-benzonitrile 95%
  • 1 g
  • $ 600.00
Total 15 raw suppliers
Chemical Property of STK393606 Edit
Chemical Property:
  • Solubility.:≤12mg/ml in DMSO;14mg/ml in dimethyl formamide 
Purity/Quality:

99% *data from raw suppliers

2-(((6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio)methyl)benzonitrile 97% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH) is a key enzyme involved in the inactivation of PGs and related eiscosanoids. It functions by catalyzing the oxidation of primary PGs to their 15-keto metabolites. Two types of 15-hydroxy PGDH have been identified: type-I is NAD+-dependent primarily using eicosanoids as substrates, while type-II uses either NAD+ or NADP+ as cofactors and bears broader substrate specificity. STK393606 is a competitive inhibitor of NAD+-dependent type-I 15-hydroxy PGDH with an IC50 value of 26.4 nM and a Ki value of 5 nM. It demonstrates selectivity for 15-hydroxy PGDH when profiled across a panel of related dehydrogenase or reductase enzymes.
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