2-Amino-2-(pyridin-3-yl)ethanol

Base Information

• Chemical Name: 2-Amino-2-(pyridin-3-yl)ethanol
• CAS No.: 372144-01-9
• Molecular Formula: C7H11N2O+
• Molecular Weight: 138.169
• Hs Code.: 2933399090
• European Community (EC) Number: 803-805-2
• DSSTox Substance ID: DTXSID00370376
• Mol file: 372144-01-9.mol

Synonyms:372144-01-9;2-amino-2-(pyridin-3-yl)ethanol;1-(3-Pyridinyl)-2-hydroxyethylamine;2-amino-2-pyridin-3-yl-ethanol;2-amino-2-pyridin-3-ylethanol;2-AMINO-2-(PYRIDIN-3-YL)ETHAN-1-OL;MFCD02683180;beta-Amino-3-pyridineethanol;2-Amino-2-(pyridin-3-yl)ethanol;SCHEMBL1515430;2-Amino-2-pyridin-3-ylmethanol;DTXSID00370376;RTBSTLCUXKGLPI-UHFFFAOYSA-N;AKOS005265300;AB12437;SB36883;BS-12615;1-(3-Pyridinyl)-2-hydroxyethylamine diHCl;FT-0770241;2-amino-2-pyridin-3-yl-ethanol, AldrichCPR;EN300-133261;F13354;A874152;-Amino-3-pyridineethanol

Chemical Property of 2-Amino-2-(pyridin-3-yl)ethanol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5780 (estimate)
• Boiling Point: 317.53°C at 760 mmHg
• Flash Point: 145.837°C
• PSA: 59.14000
• Density: 1.1315 (rough estimate)
• LogP: 0.77400
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 138.079312947
• Heavy Atom Count: 10
• Complexity: 97.6

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Pyridinyl)-2-hydroxyethylamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN=C1)C(CO)N

Technology Process of 2-Amino-2-(pyridin-3-yl)ethanol

There total 1 articles about 2-Amino-2-(pyridin-3-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-2-(pyridin-3-yl)acetic acid (110772-44-6,59966-29-9) → 2-amino-2-(pyridin-3-yl)ethanol (372144-01-9,1213080-28-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1016/j.ejmech.2017.12.095

Reference yield: 20.0%

2-amino-2-(pyridin-3-yl)ethanol (372144-01-9,1213080-28-4) + 8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a] pyridine-3-carboxylic acid (1415501-19-7) → rac-8-[(2,6-difluorobenzyl)oxy]-N-[2-hydroxy-1-(pyridin-3-yl)ethyl]-2-methylimidazo[1,2-a]-pyridine-3-carboxamide (1609164-86-4)

Guidance literature:

8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a] pyridine-3-carboxylic acid; With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

2-amino-2-(pyridin-3-yl)ethanol; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

2-amino-2-(pyridin-3-yl)ethanol (372144-01-9,1213080-28-4) → 2-[6-(5-chloro-2-fluoro-phenyl)-pyrazin-2-ylamino]-2-pyridin-3-yl-ethanol (1617545-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: neat (no solvent) / 1 h / 120 °C / Microwave irradiation

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 1,2-dimethoxyethane; water / 0.67 h / 90 °C / Inert atmosphere; Microwave irradiation

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; water;

upstream raw materials:

2-amino-2-(pyridin-3-yl)acetic acid

Downstream raw materials:

rac-8-[(2,6-difluorobenzyl)oxy]-N-[2-hydroxy-1-(pyridin-3-yl)ethyl]-2-methylimidazo[1,2-a]-pyridine-3-carboxamide

2-[6-(5-chloro-2-fluoro-phenyl)-pyrazin-2-ylamino]-2-pyridin-3-yl-ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 372144-01-9 1-(3-PYRIDINYL)-2-HYDROXYETHYLAMINE,

Send

Send

Metric Ton KG G Pound L ML

Send

Send