17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione

Base Information

• Chemical Name: 17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione
• CAS No.: 69688-15-9
• Molecular Formula: C26H38O6
• Molecular Weight: 446.57632
• Mol file: 69688-15-9.mol

Synonyms:17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione;(5β)-4,5-Dihydro Medroxy Progesterone 17-Acetate;(5β,6α)-17-(Acetyloxy)-6-Methylpregnane-3,20-dione;4,5-Dihydro-6α-Methyl-17α-hydroxyprogesterone Acetate;6α-Methyl-3,20-dioxo-5β-pregnan-17α-yl Acetate;Medroxyprogesterone acetate iMpurity F (4,5-beta-DihydroMedroxyprogesterone acetate)

Chemical Property of 17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione

Chemical Property:

• PSA: 60.44000
• LogP: 4.73510
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

(5β)-4,5-DihydroMedroxyProgesterone17-Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (5β)-4,5-Dihydro Medroxy Progesterone 17-Acetate is an impurity of Medroxyprogesterone 17-Acetate (M203560).

Technology Process of 17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione

There total 1 articles about 17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Medroxyprogesterone acetate (71-58-9) → 17α-acetoxy-6α-methyl-5β-pregnane-3,20-dione (69688-15-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1016/0039-128X(79)90126-0

upstream raw materials:

Medroxyprogesterone acetate

Refernces

• 1、 Templeton, John F.,Kumar, V. P. Sashi,Kim, Ryungsoon S.,LaBella, Frank S.. "Synthesis of Ring-A and -B Substituted 17α-Acetoxypregnan-20-one Derivatives with Potential Activity on the Digitalis Receptor in Cardiac Muscle". . p. 1361 - 1368. Retrieved 2007/10/02.