Tilmicosin

Base Information

• Chemical Name: Tilmicosin
• CAS No.: 108050-54-0
• Molecular Formula: C46H80N2O13
• Molecular Weight: 869.15
• Hs Code.: 29419090
• European Community (EC) Number: 639-676-2
• Wikipedia: Tilmicosin
• NCI Thesaurus Code: C84213
• Mol file: 108050-54-0.mol

Synonyms:Tilmicosinum [INN-Latin];Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)-;EL 870;Micotil 300;Tilmicosin [USAN:BAN:INN];Tilmicosina [INN-Spanish];Micotil (TN);Micotil;Tilmicosine [INN-French];Tilmicosin Base;Tilmicosin base (USP);Tilmicosin base (USP29);Tilmicosin Solution;

Chemical Property of Tilmicosin

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.545
• Boiling Point: 926.6 °C at 760 mmHg
• PKA: pKa (66% DMF): 7.4, 8.5(at 25℃)
• Flash Point: 514.2 °C
• PSA: 186.15000
• Density: 1.18 g/cm³
• LogP: 3.27930
• Storage Temp.: 0-6°C
• Solubility.: Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly)
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 12
• Exact Mass: 868.56604061
• Heavy Atom Count: 61
• Complexity: 1420

Purity/Quality:

99% ^*data from raw suppliers

Tilmicosin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CC(CC(C3)C)C)C)C)COC4C(C(C(C(O4)C)O)OC)OC
• Isomeric SMILES: CC[C@@H]1[C@H](/C=C(\C=C\C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O)CCN3C[C@@H](C[C@@H](C3)C)C)C)/C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
• Uses: It can be used as anti-bacterial. It is mainly used for the treatment of infection caused by pleuropneumonia, Actinobacillus, Pasteurella and mycoplasma. Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock. A Macrolide antibiotic. Macrolide antibiotic structurally related to tylosin. Antibacterial