(5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone

Base Information

Chemical Name:(5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone
CAS No.:549548-32-5
Molecular Formula:C8H13NO
Molecular Weight:139.197
Hs Code.:
DSSTox Substance ID:DTXSID901242307
Nikkaji Number:J1.886.301D

Synonyms:(5S)-5-(2-METHYL-2-PROPEN-1-YL)-2-PYRROLIDINONE;DTXSID901242307;AKOS006379200;549548-32-5;(5S)-5beta-(2-Methyl-2-propenyl)pyrrolidine-2-one

Suppliers and Price of (5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:139.099714038
Heavy Atom Count:10
Complexity:163

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=C)CC1CCC(=O)N1
Isomeric SMILES:CC(=C)C[C@@H]1CCC(=O)N1

Technology Process of (5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone

There total 1 articles about (5S)-5-(2-Methyl-2-propen-1-YL)-2-pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17342-08-4
(S)-Pyroglutaminol

: 549548-32-5
(S)-5-(2-Methyl-allyl)-pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N; DMAP / CH₂Cl₂ / 20 °C

2: 93 percent / tetrahydrofuran; diethyl ether / -78 - 0 °C

With dmap; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(03)00563-X

Reference yield: 90.0%

: 549548-32-5
(S)-5-(2-Methyl-allyl)-pyrrolidin-2-one

: 549548-34-7
1-Benzyloxy-4-(1-bromomethyl-vinyl)-benzene

: 549548-35-8
(S)-1-[2-(4-Benzyloxy-phenyl)-allyl]-5-(2-methyl-allyl)-pyrrolidin-2-one

Guidance literature:: With sodium hydride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃;
DOI:10.1016/S0040-4039(03)00563-X

Reference yield:

: 549548-32-5
(S)-5-(2-Methyl-allyl)-pyrrolidin-2-one

: 23506-90-3,31470-47-0
4-[(8aS)-7-methyl-1,2,3,5,8,8a-hexahydroindolizin-6-yl]phenol

Guidance literature:: Multi-step reaction with 5 steps

1.1: 90 percent / NaH / tetrahydrofuran; hexamethylphosphoric acid triamide / 20 °C

2.1: O₃ / methanol / -78 °C

2.2: 99 percent / Me₂S / methanol / -78 - 20 °C

3.1: 30 percent / TiCl₃(THF)3; Zn-Cu / 1,2-dimethoxy-ethane / 48 h / 80 °C

4.1: 86 percent / LiAlH₄ / tetrahydrofuran / 20 °C

5.1: 100 percent / H₂ / 5 percent Pd(OH)2-C / methanol / 20 °C

With lithium aluminium tetrahydride; titanium trichloride tris(tetrahydrofuran); hydrogen; copper; sodium hydride; ozone; zinc; palladium hydroxide - carbon; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,2-dimethoxyethane; 3.1: McMurry coupling;
DOI:10.1016/S0040-4039(03)00563-X