2,6-Dibromoterephthalic acid

Base Information

• Chemical Name: 2,6-Dibromoterephthalic acid
• CAS No.: 22191-58-8
• Molecular Formula: C₈H₄Br₂O₄
• Molecular Weight: 323.925
• Mol file: 22191-58-8.mol

Synonyms:2,6-Dibromoterephthalic acid

Chemical Property of 2,6-Dibromoterephthalic acid

Chemical Property:

• PSA: 74.60000
• LogP: 2.60800

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Dibromoterephthalic acid

There total 1 articles about 2,6-Dibromoterephthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2,6-dibromo-1,4-dimethylbenzene (66788-13-4) → 2,6-dibromoterephthalic acid (22191-58-8)

Guidance literature:

With potassium permanganate; In pyridine; water; at 110 ℃; for 12h;

DOI:10.1021/jacs.7b01650

Reference yield:

2,6-dibromoterephthalic acid (22191-58-8) → C8H2Br2Cl2O2

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; at 80 ℃; for 3h;

DOI:10.1021/jacs.7b01650

Reference yield:

2,6-dibromoterephthalic acid (22191-58-8) → 2,6-dibromoterephthalamide

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / 3 h / 80 °C

2: ammonium hydroxide / 1,4-dioxane / 12 h / 20 °C

With ammonium hydroxide; thionyl chloride; N,N-dimethyl-formamide; In 1,4-dioxane;

DOI:10.1021/jacs.7b01650

upstream raw materials:

2,6-dibromo-1,4-dimethylbenzene

Refernces