(2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid

Base Information

Chemical Name:(2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid
CAS No.:599178-66-2
Molecular Formula:C₁₇H₁₅NO₃
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID30590565
Wikidata:Q82484213
Mol file:599178-66-2.mol

Synonyms:599178-66-2;(2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid;2-Acetamido-3-(4-biphenyl)acrylic acid;(E)-2-acetamido-3-(4-phenylphenyl)prop-2-enoic acid;SCHEMBL15085946;DTXSID30590565

Suppliers and Price of (2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-ACETAMIDO-3-(4-BIPHENYL)ACRYLIC ACID 95.00%
5MG
$ 500.57

Total 4 raw suppliers

Chemical Property of (2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid

Chemical Property:

Vapor Pressure:3.8E-13mmHg at 25°C
Boiling Point:554.8°C at 760 mmHg
Flash Point:289.4°C
PSA：66.40000
Density:1.228g/cm³
LogP:3.30610
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:402

Purity/Quality:

99% ^*data from raw suppliers

2-ACETAMIDO-3-(4-BIPHENYL)ACRYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(=CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)O
Isomeric SMILES:CC(=O)N/C(=C/C1=CC=C(C=C1)C2=CC=CC=C2)/C(=O)O

Technology Process of (2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid

There total 3 articles about (2E)-2-Acetamido-3-([1,1'-biphenyl]-4-yl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.5%

: 1188995-14-3
(Z)-4-([1,10-biphenyl]-4-ylmethylene)-2-methyloxazol-5(4H)-one

: 599178-66-2
3-(1-1'-biphenyl)-2-acetylamino acrylic acid

Guidance literature:: With sodium hydroxide; In water; at 100 ℃; Inert atmosphere;

Reference yield:

: 909768-56-5
4-(4-phenylphenyl)methylene-2-methyl-5(4H)-oxazolone

: 599178-66-2
3-(1-1'-biphenyl)-2-acetylamino acrylic acid

Guidance literature:: With water; In acetone; for 8h; Reflux;

Reference yield:

: 3218-36-8
4-Phenylbenzaldehyde

: 599178-66-2
3-(1-1'-biphenyl)-2-acetylamino acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride; sodium acetate / 0.5 h / Reflux

2: water / acetone / 8 h / Reflux

With water; sodium acetate; acetic anhydride; In acetone;