4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine

Base Information

Chemical Name:4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine
CAS No.:343373-72-8
Molecular Formula:C14H14ClN3O
Molecular Weight:275.73
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40360317
Wikidata:Q82141996
Mol file:343373-72-8.mol

Synonyms:4-(6-chloro-2-phenyl-4-pyrimidinyl)morpholine;4-(6-chloro-2-phenylpyrimidin-4-yl)morpholine;343373-72-8;Bionet2_000587;Oprea1_212489;Oprea1_256728;4-(6-Chloro-2-phenyl-pyrimidin-4-yl)-morpholine;SCHEMBL1029661;DTXSID40360317;BCZUTFTXOOUHBV-UHFFFAOYSA-N;HMS1365K15;MFCD00754198;AKOS005070877;6N-344S;CS-0327665;4-(6-chloro-2-phenyl-4-pyrimidyl)morpholine;J-513614

Suppliers and Price of 4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine >95%
500mg
$ 244.00

Matrix Scientific
4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine >95%
5g
$ 698.00

Matrix Scientific
4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine >95%
1g
$ 304.00

Crysdot
4-(6-Chloro-2-phenylpyrimidin-4-yl)morpholine 95+%
1g
$ 301.00

Crysdot
4-(6-Chloro-2-phenylpyrimidin-4-yl)morpholine 95+%
5g
$ 691.00

American Custom Chemicals Corporation
4-(6-CHLORO-2-PHENYL-4-PYRIMIDINYL)MORPHOLINE 95.00%
10G
$ 1766.00

American Custom Chemicals Corporation
4-(6-CHLORO-2-PHENYL-4-PYRIMIDINYL)MORPHOLINE 95.00%
5G
$ 1233.77

American Custom Chemicals Corporation
4-(6-CHLORO-2-PHENYL-4-PYRIMIDINYL)MORPHOLINE 95.00%
1G
$ 771.89

AK Scientific
4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine
500mg
$ 379.00

Total 3 raw suppliers

Chemical Property of 4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine

Chemical Property:

Melting Point:128-130°
PSA：38.25000
LogP:2.69860
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:275.0825398
Heavy Atom Count:19
Complexity:280

Purity/Quality:

98%min ^*data from raw suppliers

4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CC(=NC(=N2)C3=CC=CC=C3)Cl

Technology Process of 4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine

There total 2 articles about 4-(6-Chloro-2-phenyl-4-pyrimidinyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072084-73-1
4-(6-chloro-2-iodopyrimidin-4-yl)morpholine

: 98-80-6
phenylboronic acid

: 343373-72-8
4-(6-chloro-2-phenyl-pyrimidin-4-yl)-morpholine

Guidance literature:: With sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride; In water; acetonitrile; for 0.75h; Microwave irradiation; Heating / reflux;

Reference yield:

: 339016-18-1
4-chloro-6-(4-morpholinyl)-2-pyrimidinamine

: 343373-72-8
4-(6-chloro-2-phenyl-pyrimidin-4-yl)-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; diiodomethane; isopentyl nitrite / tetrahydrofuran / 1 h / 67 °C

2: sodium hydrogencarbonate / bis-triphenylphosphine-palladium(II) chloride / water; acetonitrile / 0.75 h / Microwave irradiation; Heating / reflux

With copper(l) iodide; diiodomethane; sodium hydrogencarbonate; isopentyl nitrite; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; acetonitrile; 2: Suzuki Coupling;