Isoginsenoside Rh3

Base Information

• Chemical Name: Isoginsenoside Rh3
• CAS No.: 166040-90-0
• Molecular Formula: C35H58O7
• Molecular Weight: 590.83082
• Mol file: 166040-90-0.mol

Synonyms:Isoginsenoside Rh3;(20E)-Ginsenoside Rh3;3-O-beta-D-Glucopyranosyldammara-(E)-20(22),24-diene-3beta,12beta-diol

Chemical Property of Isoginsenoside Rh3

Chemical Property:

• Boiling Point: 695.0±55.0 °C(Predicted)
• PKA: 12.91±0.70(Predicted)
• PSA: 119.61000
• Density: 1.17±0.1 g/cm3(Predicted)
• LogP: 5.13000

Purity/Quality:

98%Min ^*data from raw suppliers

Isoginsenoside Rh3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isoginsenoside Rh3 is a dammarane-type triterpene monoglucoside isolated from the fruits of Panax ginseng C. A. Mey.

Technology Process of Isoginsenoside Rh3

There total 2 articles about Isoginsenoside Rh3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C64H76O11 → 3β-O-β-D-glucopyranosyl-5R,9R,13R-dammarane-(E)-20(22),24-(25)-diene-12β-ol (166040-90-0)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.joc.7b02987

Reference yield:

3β-O-(2′,3′,4′,6′-tetra-O-benzoyl-β-D-glucopyranosyl)-12β-di-O-tert-butyldimethylsilyl-5R,9R,13R-dammarane-(E)-20(22),24(25)-diene → 3β-O-β-D-glucopyranosyl-5R,9R,13R-dammarane-(E)-20(22),24-(25)-diene-12β-ol (166040-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine hydrogenfluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: potassium hydroxide / methanol / 20 °C / Inert atmosphere

With pyridine hydrogenfluoride; potassium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1021/acs.joc.7b02987