2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester

Base Information

Chemical Name:2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester
CAS No.:1041026-67-8
Molecular Formula:C17H24N2O4S
Molecular Weight:352.455
Hs Code.:

Synonyms:2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester;tert-butyl 6-tosyl-2,6-diazaspiro[3.3]heptane-2-carboxylate;tert-butyl 6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate

Suppliers and Price of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester

There total 12 articles about 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-[(4-Methylphenyl)sulfonyl]-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.4%

: 4248-19-5
tert-butyl carbazate

: 1041026-61-2
3,3-bis(bromomethyl)-1-(p-toluenesulfonyl)azetidine

: 1041026-67-8
tert-butyl 6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate

Guidance literature:: tert-butyl carbazate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

3,3-bis(bromomethyl)-1-(p-toluenesulfonyl)azetidine; In tetrahydrofuran; at 50 ℃; for 9h; Temperature;

Reference yield: 81.3%

: 4248-19-5
tert-butyl carbazate

: C₁₂H₁₅I₂NO₂S

: 1041026-67-8
tert-butyl 6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate

Guidance literature:: tert-butyl carbazate; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

C₁₂H₁₅I₂NO₂S; In N,N-dimethyl-formamide; at 60 ℃; for 8h; Temperature;

Reference yield: 72.0%

: 1041026-64-5
2-benzyl-6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane

: 24424-99-5
di-tert-butyl dicarbonate

: 1041026-67-8
tert-butyl 6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate

Guidance literature:: 2-benzyl-6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane; With formic acid; palladium 10% on activated carbon; hydrogen; In methanol; at 45 ℃; for 48h;

di-tert-butyl dicarbonate; In methanol; at 20 ℃; for 1.5h;