(S)-2-(2-CHLOROPHENYL)PYRROLIDINE

Base Information

Chemical Name:(S)-2-(2-CHLOROPHENYL)PYRROLIDINE
CAS No.:1217788-99-2
Molecular Formula:C10H12ClN
Molecular Weight:181.66
Hs Code.:
Mol file:1217788-99-2.mol

Synonyms:(S)-2-(2-CHLOROPHENYL)PYRROLIDINE;(2S)-2-(2-CHLOROPHENYL)PYRROLIDINE

Suppliers and Price of (S)-2-(2-CHLOROPHENYL)PYRROLIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of (S)-2-(2-CHLOROPHENYL)PYRROLIDINE

Chemical Property:

Boiling Point:254.1±33.0 °C(Predicted)
PKA:9.45±0.10(Predicted)
PSA：12.03000
Density:1.129±0.06 g/cm3(Predicted)
LogP:3.09330
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (S)-2-(2-CHLOROPHENYL)PYRROLIDINE

There total 3 articles about (S)-2-(2-CHLOROPHENYL)PYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 129540-25-6
2-(2-chlorophenyl)-1-pyrroline

: 1217788-99-2
(S)-2-(2-chlorophenyl)pyrrolidine

Guidance literature:: With hydrogenchloride; 2,3,4,5,6-pentahydroxy-hexanal; nicotinamide adenine dinucleotide phosphate; In aq. phosphate buffer; water; dimethyl sulfoxide; at 30 ℃; for 24h; pH=7; enantioselective reaction; Enzymatic reaction;
DOI:10.1021/acs.orglett.0c00802

Reference yield:

: (S)-1-[2-(2-chlorophenyl)-1-pyrrolidinyl]-2,2,2-trifluoro-ethanone

: 1217788-99-2
(S)-2-(2-chlorophenyl)pyrrolidine

Guidance literature:: With potassium hydroxide; In methanol; at 0 - 20 ℃; for 12.1667h; Sealed tube; Inert atmosphere;
DOI:10.1016/j.chempr.2020.02.002

Reference yield:

: 129540-25-6
2-(2-chlorophenyl)-1-pyrroline

: 823188-58-5
(R)-2-(2-chlorophenyl)pyrrolidine

: 1217788-99-2
(S)-2-(2-chlorophenyl)pyrrolidine

Guidance literature:: With diethoxymethylane; diethylzinc; ((2S,2'S)-((2-hydroxy-5-methyl-1,3-phenylene)bis(methylene))bis(pyrrolidine-1,2-diyl))bis(diphenylmethanol); In tetrahydrofuran; toluene; at 4 ℃; for 48h; Overall yield = 72 percent; Overall yield = 62 mg; Inert atmosphere;
DOI:10.1002/adsc.202001043