2,4-Dichlorobenzamide

Base Information

• Chemical Name: 2,4-Dichlorobenzamide
• CAS No.: 2447-79-2
• Molecular Formula: C7H5Cl2NO
• Molecular Weight: 190.029
• Hs Code.: 29242990
• European Community (EC) Number: 219-505-4
• NSC Number: 39528
• UNII: ZX274BU5RA
• DSSTox Substance ID: DTXSID5022190
• Nikkaji Number: J216.088I
• Wikidata: Q27295929
• ChEMBL ID: CHEMBL3989126
• Mol file: 2447-79-2.mol

Synonyms:2,4-Dichlorobenzamide;2447-79-2;Benzamide, 2,4-dichloro-;EINECS 219-505-4;UNII-ZX274BU5RA;ZX274BU5RA;AI3-09766;NSC-39528;NSC39528;2,4-dichloro-benzamide;Benzamide,2,4-dichloro-;2,4-CHLOROBENZAMIDE;SCHEMBL325007;CHEMBL3989126;DTXSID5022190;XXFUNTSOBHSMBU-UHFFFAOYSA-;STR01087;MFCD00007974;NSC 39528;AKOS003409187;AC-27895;MS-10586;LS-184925;CS-0316313;D2867;FT-0610039;A51058;A817329;Q27295929

Chemical Property of 2,4-Dichlorobenzamide

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 0.00396mmHg at 25°C
• Melting Point: 191-194 °C(lit.)
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 279.7°C at 760 mmHg
• PKA: 15.08±0.50(Predicted)
• Flash Point: 122.9°C
• PSA: 43.09000
• Density: 1.439g/cm³
• LogP: 2.79260
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 188.9748192
• Heavy Atom Count: 11
• Complexity: 163

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dichlorobenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Cl)C(=O)N

Technology Process of 2,4-Dichlorobenzamide

There total 18 articles about 2,4-Dichlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimedone (126-81-8) + N,N'-bis-(2,4-dichloro-benzoyl)-sulfur diimide (73339-77-2) → 2,4-dichlorobenzamide (2447-79-2) + 3-(2,4-Dichloro-phenyl)-8,8-dimethyl-4-oxa-1-thia-2-aza-spiro[4.5]dec-2-ene-6,10-dione (85078-64-4)

Guidance literature:

In benzene; at 20 ℃; for 2.5h;

Reference yield: 100.0%

N,N'-bis-(2,4-dichloro-benzoyl)-sulfur diimide (73339-77-2) + 1,3-diphenylpropanedione (120-46-7,61346-73-4) → 2,4-dichlorobenzamide (2447-79-2) + [2-Benzoyl-5-(2,4-dichloro-phenyl)-[1,3,4]oxathiazol-2-yl]-phenyl-methanone (85078-60-0)

Guidance literature:

In benzene; at 20 ℃; for 2.5h;

Reference yield: 97.3%

2,4-dichlorobenzoyl chloride (89-75-8) → 2,4-dichlorobenzamide (2447-79-2)

Guidance literature:

With ammonium hydroxide; at -10 - 20 ℃; for 1.5h; Concentration;

upstream raw materials:

2,4-dichlorobenzoyl chloride

2,4-dichlorobenzylnitrile

dimedone

N,N'-bis-(2,4-dichloro-benzoyl)-sulfur diimide

Downstream raw materials:

2,4-Dichloro-N-[1-dimethylamino-eth-(E)-ylidene]-benzamide

N-(2,4-dichlorophenyl)-N'-methyl-urea

2,4-dichloro-benzoic acid-(chloromethyl-amide)

1-(2,4-dichlorobenzoyl)-3-(2,2-dimethyl-4-oxo-4H-benzo[1,3]dioxin-7-yl)urea