6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid

Base Information

Chemical Name:6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid
CAS No.:26893-20-9
Molecular Formula:C10H5Cl2NO3
Molecular Weight:258.0576
Hs Code.:
DSSTox Substance ID:DTXSID801233951
Mol file:26893-20-9.mol

Synonyms:6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid;26893-20-9;51726-82-0;6,7-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;6,7-dichloro-4-oxo-1H-quinoline-3-carboxylic acid;starbld0030212;DTXSID801233951;AKOS022496127;SB71074;EN300-1692996;6,7-Dichloro-4-hydroxy-3-quinolinecarboxylic acid;Z2049894621

Suppliers and Price of 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6,7-Dichloro-4-hydroxyquinoline-3-carboxylicacid 95+%
1g
$ 698.00

Chemenu
6,7-dichloro-4-hydroxyquinoline-3-carboxylicacid 95%
1g
$ 660.00

Alichem
6,7-Dichloro-4-hydroxyquinoline-3-carboxylicacid
1g
$ 619.12

Total 5 raw suppliers

Chemical Property of 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid

Chemical Property:

PSA：70.16000
LogP:2.53310
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:256.9646484
Heavy Atom Count:16
Complexity:369

Purity/Quality:

99% ^*data from raw suppliers

6,7-Dichloro-4-hydroxyquinoline-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C2C(=CC(=C1Cl)Cl)NC=C(C2=O)C(=O)O

Technology Process of 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid

There total 2 articles about 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 26892-93-3,122224-58-2
ethyl 6,7-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate

: 26893-20-9,51726-82-0
base

Guidance literature:: With sodium hydroxide;
DOI:10.1080/07328319808004315

Reference yield:

: 26893-20-9
6,7-Dichloro-4-hydroxy-quinoline-3-carboxylic acid

Guidance literature:: entspr. Ester III;

Reference yield:

: 26893-20-9,51726-82-0
base

: 213275-21-9
6,7-dichloro-1,4-dihydro-4-oxo-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)quinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (NH₄)2SO₄ / 1,2-dichloro-ethane / 5 h / Heating

2: 60 percent / trimethylsilyl triflate / 1,2-dichloro-ethane / 3.5 h / Ambient temperature

With ammonium sulfate; trimethylsilyl trifluoromethanesulfonate; In 1,2-dichloro-ethane;
DOI:10.1080/07328319808004315