ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Base Information

Chemical Name:ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride
CAS No.:866459-01-0
Molecular Formula:C15H19ClN2O2
Molecular Weight:294.781
Hs Code.:
Mol file:866459-01-0.mol

Synonyms:ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Suppliers and Price of ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Chemical Property:

PSA：43.26000
LogP:2.98090

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

There total 3 articles about ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 866459-02-1
tert-butyl 5-(2-ethoxy-2-oxoethyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate

: 866459-01-0
ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃;
DOI:10.1016/j.bmcl.2012.12.050

Reference yield:

: 627869-56-1
tert‐butyl 1,3,4,5‐tetrahydro‐2H‐pyrido[4,3‐b]indole‐2‐carboxylate

: 866459-01-0
ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 20 °C / Reflux

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; In 1,4-dioxane; acetone;
DOI:10.1016/j.bmcl.2012.12.050

Reference yield:

: 6208-60-2
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

: 866459-01-0
ethyl 2-(3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C

2: caesium carbonate / N,N-dimethyl-formamide / 1 h / 80 °C

3: hydrogenchloride / dichloromethane; 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; caesium carbonate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm400122f