(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Base Information

Chemical Name:(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester
CAS No.:73275-76-0
Molecular Formula:C24H31F3O6
Molecular Weight:472.4945
Hs Code.:
Mol file:73275-76-0.mol

Synonyms:

Suppliers and Price of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Fluprostenol methyl ester ≥98%
5mg
$ 273.00

Cayman Chemical
Fluprostenol methyl ester ≥98%
10mg
$ 485.00

Cayman Chemical
Fluprostenol methyl ester ≥98%
1mg
$ 61.00

AK Scientific
(+)-Fluprostenolmethylester
10mg
$ 704.00

AK Scientific
(+)-Fluprostenolmethylester
5mg
$ 440.00

AK Scientific
(+)-Fluprostenolmethylester
1mg
$ 175.00

Total 1 raw suppliers

Chemical Property of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

Chemical Property:

Vapor Pressure:8.91E-14mmHg at 25°C
Boiling Point:568.8°Cat760mmHg
Flash Point:297.8°C
PSA：96.22000
Density:1.281g/cm³
LogP:3.64880

Purity/Quality:

≥98% ^*data from raw suppliers

Fluprostenol methyl ester ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

There total 1 articles about (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54276-17-4
(+)-fluprostenol

: 18107-18-1
diazomethyl-trimethyl-silane

: 73275-76-0
(Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate

Guidance literature:: In methanol; at 0 ℃;

Reference yield:

: 69739-34-0
t-butyldimethylsiyl triflate

: 73275-76-0
(Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate

: (Z)-methyl 7-((1R,2R,3R,5S)-3,5-bis(tert-butyldimethylsilyloxy)-2-((R,E)-3-(tert-butyldimethylsilyloxy)-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at 0 - 20 ℃; for 12.5h;

Reference yield:

: 73275-76-0
(Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate

: (Z)-7-((1R,2R,3R,5S)-3,5-bis(tert-butyldimethylsilyloxy)-2-((R,E)-3-(tert-butyldimethylsilyloxy)-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2,6-dimethylpyridine / dichloromethane / 12.5 h / 0 - 20 °C

2: lithium hydroxide monohydrate / methanol; tetrahydrofuran; water / 20 °C

With 2,6-dimethylpyridine; lithium hydroxide monohydrate; In tetrahydrofuran; methanol; dichloromethane; water;