(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Base Information

Chemical Name:(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
CAS No.:196085-84-4
Molecular Formula:C₁₄H₂₃NO₄
Molecular Weight:269.341
Hs Code.:
Mol file:196085-84-4.mol

Synonyms:(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Suppliers and Price of (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-aceticAcidtert-ButylEster
10mg
$ 155.00

Crysdot
tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 95+%
1g
$ 2972.00

American Custom Chemicals Corporation
TERT-BUTYL-2-((4R,6S)-6-(CYANOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE 95.00%
5MG
$ 503.73

Alichem
tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
1g
$ 2520.00

Total 12 raw suppliers

Chemical Property of (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Chemical Property:

Boiling Point:364.1±17.0 °C(Predicted)
PSA：68.55000
Density:1.016±0.06 g/cm3(Predicted)
LogP:2.54208
Storage Temp.:2-8°C

Purity/Quality:

NLT 98% ^*data from raw suppliers

(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-aceticAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

Technology Process of (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

There total 52 articles about (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%