2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine

Base Information

Chemical Name:2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine
CAS No.:300552-47-0
Molecular Formula:C18H21N3O2
Molecular Weight:311.384
Hs Code.:2933990090
Mol file:300552-47-0.mol

Synonyms:2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine;tert-Butyl 2-phenyl-7,8-dihydropyrido[4,3-d]pyriMidine-6(5H)-carboxylate

Suppliers and Price of 2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl2-phenyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate 95+%
1g
$ 339.00

Chemcia Scientific
2-Phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylicacidtert-butylester ＞98%
1 G
$ 300.00

Total 4 raw suppliers

Chemical Property of 2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine

Chemical Property:

PSA：55.32000
LogP:3.37470
Storage Temp.:2-8°C

Purity/Quality:

≥99% ^*data from raw suppliers

tert-Butyl2-phenyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine

There total 3 articles about 2-Phenyl-6-boc-7,8-dihydro-5H-pyrido[4,3-d]pyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.15%

: 1202645-17-7
3-dimethylaminomethylene-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 1670-14-0
benzamidine monohydrochloride

: 300552-47-0
tert-butyl 2-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate

Guidance literature:: With triethylamine; In ethanol; at 80 ℃; for 2h;

Reference yield:

: 1202645-17-7
3-dimethylaminomethylene-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 74222-83-6,206752-36-5
benzamidine hydrochloride hydrate

: 300552-47-0
tert-butyl 2-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate

: 300550-04-3
{4-[2-(1R-Hydroxy-ethyl)-pyrimidin-4-yl]-2R,6S-dimethyl-piperazin-1-yl}-(2-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-methanone

Guidance literature:: With sodium ethanolate; In ethanol; ethyl acetate;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 300552-47-0
tert-butyl 2-phenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; 1,4-dioxane / 16 h / 120 °C

2: triethylamine / ethanol / 2 h / 80 °C

With triethylamine; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;