3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester

Base Information

• Chemical Name: 3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester
• CAS No.: 960521-55-5
• Molecular Formula: C24H31NO4
• Molecular Weight: 397.514
• Mol file: 960521-55-5.mol

Synonyms:3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester

Chemical Property of 3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester

Chemical Property:

• PSA: 59.75000
• LogP: 5.69100

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester

There total 1 articles about 3-Furancarboxylic acid, 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-[(1-methylethyl)amino]-5-phenyl-3-furancarboxylate (960521-54-4) + trans-4-methylcyclohexanecarbonyl chloride (55930-23-9) → ethyl 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-3-furancarboxylate (960521-55-5)

Guidance literature:

With triethylamine; In dichloromethane; at 45 ℃; for 24h; Under nitrogen;

Reference yield:

ethyl 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-3-furancarboxylate (960521-55-5) → 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-3-furancarboxylic acid (960522-02-5)

Guidance literature:

ethyl 2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-3-furancarboxylate; With lithium hydroxide; In tetrahydrofuran; ethanol; water; at 20 ℃; for 24h;

With hydrogenchloride; In tetrahydrofuran; ethanol; water;

upstream raw materials:

ethyl 2-[(1-methylethyl)amino]-5-phenyl-3-furancarboxylate

trans-4-methylcyclohexanecarbonyl chloride

Downstream raw materials:

2-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-phenyl-3-furancarboxylic acid