3-Pyrrolidineacetic acid, Methyl ester, hydrochloride

Base Information

• Chemical Name: 3-Pyrrolidineacetic acid, Methyl ester, hydrochloride
• CAS No.: 1126794-67-9
• Molecular Formula: C₇H₁₃NO₂*ClH
• Molecular Weight: 179.647
• Mol file: 1126794-67-9.mol

Synonyms:3-Pyrrolidineacetic acid, Methyl ester, hydrochloride;Methyl 3-pyrrolidinylacetate hydrochloride (SALTDATA: HCl);3-Pyrrolidineacetic acid methyl ester HCl

Chemical Property of 3-Pyrrolidineacetic acid, Methyl ester, hydrochloride

Chemical Property:

• PSA: 38.33000
• LogP: 1.28980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

3-PyrrolidineaceticAcidMethylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Pyrrolidineacetic Acid Methyl Ester Hydrochloride is an intermediate in the preparation of quinoxaline-piperidine derivatives as ORL1 receptor modulators useful in the treatment of diseases.

Technology Process of 3-Pyrrolidineacetic acid, Methyl ester, hydrochloride

There total 1 articles about 3-Pyrrolidineacetic acid, Methyl ester, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 3-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate (890849-27-1) → (S)-methyl 2-(pyrrolidin-3-yl)acetate hydrochloride (1126794-67-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 25 - 50 ℃; for 2h;

upstream raw materials:

tert-butyl 3-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate

Refernces