5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro-

Base Information

• Chemical Name: 5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro-
• CAS No.: 40421-03-2
• Molecular Formula: C15H10Br2ClNO
• Molecular Weight: 415.512
• Mol file: 40421-03-2.mol

Synonyms:5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro-

Chemical Property of 5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro-

Chemical Property:

• Melting Point: 169 - 172 °C
• PSA: 20.31000
• LogP: 6.13410

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro-

There total 2 articles about 5H-Dibenz[B,F]Azepine-5-Carbonyl Chloride, 10,11-DibroMo-10,11-Dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

trans-10-bromo-10,11-dihydro-11-hydroxy-5H-dibenzazepine-5-carbonyl chloride (41359-12-0,66849-41-0) → 5H-dibenz[b,f]azepine-5-carbonylchloride (33948-22-0) + trans-10,11-dibromo-10,11-dihydro-5H-dibenzazepine-5-carbonyl chloride (40421-03-2,56875-24-2)

Guidance literature:

With hydrogen bromide; In chloroform; at 10 ℃; for 1.5h; Product distribution; variaton of solvents and reactant;

DOI:10.1021/ja00210a039

Reference yield:

1a,10b-dihydro-6H-dibenzooxirenoazepine-6-carbonyl chloride (41359-09-5) → 5H-dibenz[b,f]azepine-5-carbonylchloride (33948-22-0) + trans-10,11-dibromo-10,11-dihydro-5H-dibenzazepine-5-carbonyl chloride (40421-03-2,56875-24-2)

Guidance literature:

With hydrogen bromide; In chloroform; at 10 ℃; for 3h;

DOI:10.1021/ja00210a039

Reference yield: 65.0%

trans-10,11-dibromo-10,11-dihydro-5H-dibenzazepine-5-carbonyl chloride (40421-03-2,56875-24-2) → 5H-dibenz[b,f]azepine-5-carbonylchloride (33948-22-0)

Guidance literature:

In various solvent(s); at 25 ℃; for 24h;

DOI:10.1021/ja00210a039

upstream raw materials:

1a,10b-dihydro-6H-dibenzooxirenoazepine-6-carbonyl chloride

trans-10-bromo-10,11-dihydro-11-hydroxy-5H-dibenzazepine-5-carbonyl chloride

Downstream raw materials:

10-methoxy-5H-dibenzo[b,f]azepine

5H-dibenz[b,f]azepine-5-carbonylchloride