3-(3,4-DIMETHOXYPHENYL)PYRAZOLE

Base Information

• Chemical Name: 3-(3,4-DIMETHOXYPHENYL)PYRAZOLE
• CAS No.: 154257-70-2
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.228
• Hs Code.: 2933199090
• Mol file: 154257-70-2.mol

Synonyms:3-(3,4-DIMETHOXYPHENYL)PYRAZOLE;BUTTPARK 30\03-26;3-(3,4-Dimethoxy-phenyl)-1H-pyrazole;1,2-Dimethoxy-4-(1H-pyrazol-3-yl)benzene;3-(3,4-dimethoxyphenyl)-2H-pyrazole

Chemical Property of 3-(3,4-DIMETHOXYPHENYL)PYRAZOLE

Chemical Property:

• PSA: 47.14000
• LogP: 2.09390

Purity/Quality:

98%min ^*data from raw suppliers

3-(3,4-Dimethoxyphenyl)-1H-pyrazole ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3,4-DIMETHOXYPHENYL)PYRAZOLE

There total 9 articles about 3-(3,4-DIMETHOXYPHENYL)PYRAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one (127172-22-9) → 3-(3,4-dimethoxyphenyl)-1H-pyrazole (154257-70-2)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1155/2019/2467970

Reference yield:

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one (10548-77-3) → 3-(3,4-dimethoxyphenyl)-1H-pyrazole (154257-70-2)

Guidance literature:

With hydrazine hydrate; potassium hydroxide; In ethylene glycol; at 150 ℃; for 16h;

DOI:10.1002/adsc.201901641

Reference yield:

2-(2,6-dimethoxyphenoxy)-1-(3,4-dimethoxyphenyl)-3-hydroxypropan-1-one → 3-(3,4-dimethoxyphenyl)-1H-pyrazole (154257-70-2)

Guidance literature:

With hydrazine hydrate; potassium hydroxide; In ethylene glycol; at 150 ℃; for 16h;

DOI:10.1002/adsc.201901641

upstream raw materials:

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one

1-(3,4-dimethoxyphenyl)ethanone

ethyl-3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Downstream raw materials:

1-(3-(3,4-dimethoxyphenyl)-1H-pyrazol-1-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone

1-(3-(3,4-dimethoxyphenyl)-1H-pyrazol-1-yl)-2-(4-fluorophenyl)-2-methoxyethanone