4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate

Base Information

• Chemical Name: 4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate
• CAS No.: 10376-42-8
• Molecular Formula: C₃₂H₅₂O₂
• Molecular Weight: 468.764
• Mol file: 10376-42-8.mol

Synonyms:4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate

Chemical Property of 4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate

Chemical Property:

• Melting Point: 108 - 110 °C (methanol)
• PSA: 26.30000
• LogP: 8.59560

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate

There total 13 articles about 4α,14-Dimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

jatrocurin → cycloeucalenyl acetate (10376-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 20 mg / 5percent aq. KOH / methanol / 8.5 h / Heating

2: 3 mg / pyridine / 24 h / Ambient temperature

With pyridine; potassium hydroxide; In methanol;

Reference yield:

cycloeucalenol (469-39-6,122441-94-5,127243-83-8) → cycloeucalenol acetate (10376-42-8)

Guidance literature:

With acetylated;

DOI:10.1016/0040-4039(81)80127-X

Reference yield:

cyclohomonervilol (78330-51-5) → cycloeucalenol acetate (10376-42-8)

Guidance literature:

Multi-step reaction with 7 steps

1: acetylated

2: 1.) osmium tetroxide, 2.) HIO₄

3: haloform reaction, followed by methylation

4: 2.)LiAlH₄

6: 2.) aq.AcOH / 1.) DMSO, 170 -180 deg C

7: acetylated

With osmium(VIII) oxide; lithium aluminium tetrahydride; acetylated; acetic acid; periodic acid;

DOI:10.1016/0040-4039(81)80127-X

upstream raw materials:

acetic anhydride

cycloeucalenol

cyclohomonervilol

(R)-2-Isopropyl-5-[(3S,4S,9S,10R,13R,14S,17R)-4,13,14-trimethyl-3-(tetrahydro-pyran-2-yloxy)-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-17-yl]-hexan-1-ol

Downstream raw materials:

29-nor-cycloartanol

Refernces

• 1、 Talapatra, Sunil K.,Mandal, Kabita,Talapatra, Bani. "Jatrocurin, a New Tetracyclic Triterpene from Jatropha curcas". . p. 543 - 548. Retrieved 2007/10/02.