2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride

Base Information

• Chemical Name: 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride
• CAS No.: 864289-85-0
• Molecular Formula: C₂₇H₄₁N₅O₂
• Molecular Weight: 467.655
• Mol file: 864289-85-0.mol

Synonyms:2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride;C 021 dihydrochloride;CCR4 Antagonist

Chemical Property of 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride

Chemical Property:

• PSA: 62.75000
• LogP: 5.31230
• Storage Temp.: Desiccate at RT
• Solubility.: Soluble in DMSO

Purity/Quality:

97% ^*data from raw suppliers

C 021 dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride

There total 1 articles about 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinaminedihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

4-piperidinopiperidin (4897-50-1) + 2-chloro-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine (864293-09-4) → CCR4 (864289-85-0)

Guidance literature:

In butan-1-ol; Heating;

DOI:10.1016/j.bmc.2008.05.036

upstream raw materials:

4-piperidinopiperidin

2-chloro-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine