2-Bromo-6-iodo-4-methylaniline

Base Information

Chemical Name:2-Bromo-6-iodo-4-methylaniline
CAS No.:289038-12-6
Molecular Formula:C7H7BrIN
Molecular Weight:311.948
Hs Code.:
DSSTox Substance ID:DTXSID10464891
Wikidata:Q82290432
Mol file:289038-12-6.mol

Synonyms:2-BROMO-6-IODO-4-METHYLANILINE;289038-12-6;2-BROMO-4-METHYL-6-IODOANILINE;Benzenamine, 2-bromo-6-iodo-4-methyl-;SCHEMBL24629872;DTXSID10464891;AKOS017547754;FT-0740136

Suppliers and Price of 2-Bromo-6-iodo-4-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-6-iodo-4-methylaniline 95+%
5g
$ 823.00

Chemcia Scientific
2-Bromo-6-iodo-4-methyl-phenylamine 95%
1 G
$ 395.00

American Custom Chemicals Corporation
2-BROMO-6-IODO-4-METHYLANILINE 95.00%
5MG
$ 500.93

Alichem
2-Bromo-6-iodo-4-methylaniline
1g
$ 455.52

Total 5 raw suppliers

Chemical Property of 2-Bromo-6-iodo-4-methylaniline

Chemical Property:

Boiling Point:304.8±42.0 °C(Predicted)
PKA:0.91±0.10(Predicted)
PSA：26.02000
Density:2.133±0.06 g/cm3(Predicted)
LogP:3.52550
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:310.88066
Heavy Atom Count:10
Complexity:120

Purity/Quality:

98% ^*data from raw suppliers

2-Bromo-6-iodo-4-methylaniline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)I)N)Br

Technology Process of 2-Bromo-6-iodo-4-methylaniline

There total 3 articles about 2-Bromo-6-iodo-4-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-bromo-p-toluidine: 583-68-6
2-bromo-p-toluidine

: 289038-12-6
2-bromo-6-iodo-4-methylaniline

Guidance literature:: With iodine; silver sulfate; In ethanol; at 20 ℃;
DOI:10.1016/j.tet.2015.10.002

Reference yield:

: 814-68-6,25189-84-8
acryloyl chloride

: (2-bromo-6-iodo-4-methyl-phenyl)-methyl-amine

: 289038-12-6
2-bromo-6-iodo-4-methylaniline

: N-(2-bromo-6-iodo-4-methyl-phenyl)-N-methyl-acrylamide

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;
DOI:10.1016/j.tet.2004.05.116

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 289038-12-6
2-bromo-6-iodo-4-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; aluminum (III) chloride / dichloromethane / 20 °C

2: iodine; silver sulfate / ethanol / 20 °C

With aluminum (III) chloride; N-Bromosuccinimide; iodine; silver sulfate; In ethanol; dichloromethane;
DOI:10.1016/j.tet.2015.10.002