4,7,8-Trichlorocinnoline

Base Information

• Chemical Name: 4,7,8-Trichlorocinnoline
• CAS No.: 856179-55-0
• Molecular Formula: C₈H₃Cl₃N₂
• Molecular Weight: 233.484
• Hs Code.: 2933990090
• Mol file: 856179-55-0.mol

Synonyms:4,7,8-Trichlorocinnoline

Chemical Property of 4,7,8-Trichlorocinnoline

Chemical Property:

• PSA: 25.78000
• LogP: 3.59000

Purity/Quality:

97% ^*data from raw suppliers

4,7,8-Trichlorocinnoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,7,8-Trichlorocinnoline

There total 2 articles about 4,7,8-Trichlorocinnoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7,8-dichloro-1H-cinnolin-4-one (18514-99-3) → 4,7,8-Trichlor-cinnolin (856179-55-0)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate;

DOI:10.1039/jr9470000227

Reference yield:

2,3-dichloro-6-acetyl-aniline (777067-75-1) → 4,7,8-Trichlor-cinnolin (856179-55-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HCl / Diazotization_.anschliessend Erwaermen

2: POCl₃; PCl₅

With hydrogenchloride; phosphorus pentachloride; trichlorophosphate;

DOI:10.1039/jr9470000227

Reference yield:

4,7,8-Trichlor-cinnolin (856179-55-0) + phenol (108-95-2,27073-41-2) → 7,8-dichloro-4-phenoxy-cinnoline (854888-82-7)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/jr9470000227

upstream raw materials:

7,8-dichloro-1H-cinnolin-4-one

2,3-dichloro-6-acetyl-aniline

Downstream raw materials:

7,8-dichloro-4-phenoxy-cinnoline