5-Fluoro-2-nitro-4-(trifluoromethyl)aniline

Base Information

Chemical Name:5-Fluoro-2-nitro-4-(trifluoromethyl)aniline
CAS No.:428871-73-2
Molecular Formula:C7H4F4N2O2
Molecular Weight:224.115
Hs Code.:2921420090
DSSTox Substance ID:DTXSID80443431
Wikidata:Q82261243
Mol file:428871-73-2.mol

Synonyms:5-fluoro-2-nitro-4-(trifluoromethyl)aniline;428871-73-2;4-Amino-2-fluoro-5-nitrobenzotrifluoride;SCHEMBL1192979;DTXSID80443431;MFCD09907681;AT26637;SB77032;PS-10498;CS-0452444;5-fluoro-2-nitro-4-trifluoromethyl-phenylamine;5-fluoro-2-nitro-4-tri-fluoromethyl-phenylamine;EN300-9452992

Suppliers and Price of 5-Fluoro-2-nitro-4-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-fluoro-2-nitro-4-(trifluoromethyl)aniline
50mg
$ 65.00

TRC
5-fluoro-2-nitro-4-(trifluoromethyl)aniline
10mg
$ 45.00

SynQuest Laboratories
4-Amino-2-fluoro-5-nitrobenzotrifluoride
1 g
$ 184.00

SynQuest Laboratories
4-Amino-2-fluoro-5-nitrobenzotrifluoride
250 mg
$ 74.00

Crysdot
5-Fluoro-2-nitro-4-(trifluoromethyl)aniline 97%
1g
$ 322.00

Chemcia Scientific
5-Fluoro-2-nitro-4-trifluoromethyl-phenylamine 95%
5 G
$ 650.00

American Custom Chemicals Corporation
5-FLUORO-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE 95.00%
1G
$ 744.86

American Custom Chemicals Corporation
5-FLUORO-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE 95.00%
250MG
$ 644.45

Total 8 raw suppliers

Chemical Property of 5-Fluoro-2-nitro-4-(trifluoromethyl)aniline

Chemical Property:

Boiling Point:281.7±40.0 °C(Predicted)
PKA:-3.68±0.25(Predicted)
PSA：71.84000
Density:1.586±0.06 g/cm3(Predicted)
LogP:3.43930
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:224.02089002
Heavy Atom Count:15
Complexity:252

Purity/Quality:

99.00% ^*data from raw suppliers

5-fluoro-2-nitro-4-(trifluoromethyl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C(=CC(=C1[N+](=O)[O-])N)F)C(F)(F)F

Technology Process of 5-Fluoro-2-nitro-4-(trifluoromethyl)aniline

There total 3 articles about 5-Fluoro-2-nitro-4-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1026828-94-3
N-(5-fluoro-2-nitro-4-trifluoromethyl-phenyl)-acetamide

: 428871-73-2
5-fluoro-2-nitro-4-(trifluoromethyl)aniline

Guidance literature:: N-(5-fluoro-2-nitro-4-trifluoromethyl-phenyl)-acetamide; With hydrogenchloride; In water; for 3h; Reflux;

With sodium hydrogencarbonate; In water; at 0 ℃; pH=8;

Reference yield:

: 3-fluoro-4-trifluoromethylaniline

: 428871-73-2
5-fluoro-2-nitro-4-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: 12 h / 25 °C

2: concd. H₂SO₄, concd. HNO₃ / 0 - 20 °C

3: concd. HCl / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jm00022a003

Reference yield:

: 1026932-27-3
N-(3-fluoro-4-trifluoromethyl-phenyl)-acetamide

: 428871-73-2
5-fluoro-2-nitro-4-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: concd. H₂SO₄, concd. HNO₃ / 0 - 20 °C

2: concd. HCl / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jm00022a003