6-Bromo-8-methylquinolin-2(1H)-one

Base Information

Chemical Name:6-Bromo-8-methylquinolin-2(1H)-one
CAS No.:99465-08-4
Molecular Formula:C₁₀H₈BrNO
Molecular Weight:238.084
Hs Code.:2933790090
DSSTox Substance ID:DTXSID70550805
Mol file:99465-08-4.mol

Synonyms:6-BROMO-8-METHYLQUINOLIN-2(1H)-ONE;99465-08-4;6-bromo-8-methyl-1H-quinolin-2-one;6-bromo-8-methyl-1,2-dihydroquinolin-2-one;SCHEMBL7264778;DTXSID70550805;TQP0430;NRTSKZZQWFZTTG-UHFFFAOYSA-N;AC7497;MFCD11226924;6-bromo-8-methyl-2-(1H)-quinolone;AKOS013528675;MB09777;SY036031;CS-0232788;EN300-128714;A916246;Z1209414437

Suppliers and Price of 6-Bromo-8-methylquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Bromo-8-methylquinolin-2(1H)-one 97%
1g
$ 371.00

Chemenu
6-Bromo-8-methylquinolin-2(1H)-one 95%
1g
$ 431.00

AK Scientific
6-Bromo-8-methylquinolin-2(1H)-one
10g
$ 2582.00

Total 4 raw suppliers

Chemical Property of 6-Bromo-8-methylquinolin-2(1H)-one

Chemical Property:

Melting Point:280-281 °C
Boiling Point:387.4±42.0 °C(Predicted)
PKA:10.77±0.70(Predicted)
PSA：33.12000
Density:1.540±0.06 g/cm3(Predicted)
LogP:3.01130
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:236.97893
Heavy Atom Count:13
Complexity:251

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-8-methylquinolin-2(1H)-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC2=C1NC(=O)C=C2)Br

Technology Process of 6-Bromo-8-methylquinolin-2(1H)-one

There total 5 articles about 6-Bromo-8-methylquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 99465-17-5
trans-N-(4-bromo-2-methylphenyl)-3-ethoxy-2-propenamide

: 99465-08-4
6-bromo-8-methyl-2(1H)-quinolinone

Guidance literature:: With sulfuric acid; for 16h; Yield given; Ambient temperature;
DOI:10.1021/jm00118a034

Reference yield:

: 99455-14-8
6-Bromo-2-chloro-8-methylquinoline

: 99465-08-4
6-bromo-8-methyl-quinolin-2-ol

Guidance literature:: With sulfuric acid; water; at 180 ℃;
DOI:10.1021/ja01165a063

Reference yield:

: 583-75-5
4-Bromo-2-methylaniline

: 99465-08-4
6-bromo-8-methyl-2(1H)-quinolinone

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / pyridine / 0.5 h / 0 °C

2: 98percent H₂SO₄ / 16 h / Ambient temperature

With sulfuric acid; In pyridine;
DOI:10.1021/jm00118a034