16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone

Base Information

• Chemical Name: 16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone
• CAS No.: 25092-28-8
• Molecular Formula: C₂₆H₃₂O₆
• Molecular Weight: 440.536
• Mol file: 25092-28-8.mol

Synonyms:(16α)-21-Acetyloxy-16,17-dihydroxy-16,17-O-isopropylidene-pregna-1,4,9(11)-triene-3,20-dione;16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone

Chemical Property of 16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone

Chemical Property:

• Melting Point: 214.5-216 °C(Solv: water (7732-18-5); acetone (67-64-1))
• Boiling Point: 570.5±50.0 °C(Predicted)
• PSA: 78.90000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 3.84680

Purity/Quality:

98% ^*data from raw suppliers

(16α)-21-Acetyloxy-16,17-dihydroxy-16,17-O-isopropylidene-pregna-1,4,9(11)-triene-3,20-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the preparation of antiinflammatory compounds.

Technology Process of 16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone

There total 1 articles about 16α,17,21-Trihydroxy-pregna-1,4,9(11)-triene-3,20-dione Cyclic 16,17-Acetate with Acetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 21-Acetoxy-16α,17α-isopropylidendioxy-pregna-1,4,9(11)-trien-3,20-dion (25092-28-8)

Guidance literature:

aus 21-Acetoxy-11β-hydroxy-16α,17α-isopropylidendioxy-pregna-1,4-dien-3,20-dion, N-Brom-acetamid, SO2 in Py.;

DOI:10.1016/S0039-128X(63)80116-6