(E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

Base Information

Chemical Name:(E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride
CAS No.:344402-16-0
Molecular Formula:C₁₁H₁₁ClO₃
Molecular Weight:226.66
Hs Code.:
European Community (EC) Number:673-202-5
Nikkaji Number:J2.862.211B
Wikidata:Q76310599
Mol file:344402-16-0.mol

Synonyms:344402-16-0;(E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride;(e)-3-(2,5-dimethoxyphenyl)acryloyl chloride;(E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl chloride;2,5-dimethoxycinnamoyl chloride;3-(2,5-Dimethoxyphenyl)acryloyl chloride;(2E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl chloride;3-(2,5-DIMETHOXYPHENYL)-2-PROPENOYLCHLORIDE;SCHEMBL9256668;MFCD03424738;AKOS024254391;NS-02851;3-(2,5-dimethoxy-phenyl)-acryloyl chloride;3-(2,5-dimethoxyphenyl)-2-propenoyl chloride;(E)-3-(2,5-Dimethoxy-phenyl)-acryloylchloride;A912516;METHYL2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE

Suppliers and Price of (E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(e)-3-(2,5-Dimethoxyphenyl)acryloylChloride
10mg
$ 45.00

Crysdot
(E)-3-(2,5-Dimethoxy-phenyl)-acryloylchloride 95+%
1g
$ 524.00

CHESS?
CC000174:3-(2,5-Dimethoxy-phenyl)-acryloylchloride 95
5 g
$ 600.00

Atlantic Research Chemicals
3-(2,5-Dimethoxyphenyl)acryloylchloride 95%
1gm:
$ 236.82

American Custom Chemicals Corporation
(E)-3-(2,5-DIMETHOXY-PHENYL)-ACRYLOYL CHLORIDE 95.00%
5MG
$ 497.21

Total 5 raw suppliers

Chemical Property of (E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

Chemical Property:

Boiling Point:351.4±27.0 °C(Predicted)
Density:1.212±0.06 g/cm3(Predicted)
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:226.0396719
Heavy Atom Count:15
Complexity:240

Purity/Quality:

97% ^*data from raw suppliers

(e)-3-(2,5-Dimethoxyphenyl)acryloylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)OC)C=CC(=O)Cl
Isomeric SMILES:COC1=CC(=C(C=C1)OC)/C=C/C(=O)Cl

Technology Process of (E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

There total 4 articles about (E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10538-51-9
2,5-dimethoxycinnamic acid

: 1038808-93-3,344402-16-0
2,5-dimethoxycinnamoyl chloride

Guidance literature:: With thionyl chloride; at 45 ℃; for 1h;

Reference yield:

: 38489-74-6
trans-2,5-dimethoxycinnamic acid

: 344402-16-0
(E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

Guidance literature:: With thionyl chloride; for 4h; Reflux;
DOI:10.1007/s00044-013-0741-y

Reference yield:

: 93-02-7
2,5-dimethoxybenzaldehyde

: 344402-16-0
(E)-3-(2,5-Dimethoxy-phenyl)-acryloyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutylammomium bromide; potassium carbonate / water / Microwave irradiation

2: thionyl chloride / 4 h / Reflux

With thionyl chloride; tetrabutylammomium bromide; potassium carbonate; In water; 1: |Knoevenagel Condensation;
DOI:10.1007/s00044-013-0741-y