benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate

Base Information

• Chemical Name: benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate
• CAS No.: 1352328-67-6
• Molecular Formula: C33H48O4
• Molecular Weight: 508.73
• Mol file: 1352328-67-6.mol

Synonyms:benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate;OCA-G1

Chemical Property of benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate

Chemical Property:

• Boiling Point: 612.6±50.0 °C(Predicted)
• PKA: 14.19±0.70(Predicted)
• PSA: 66.76000
• Density: 1.127±0.06 g/cm3(Predicted)
• LogP: 6.69290

Purity/Quality:

99% ^*data from raw suppliers

(R)-Benzyl4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate

There total 1 articles about benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3α-hydroxy-6-ethylidene-7-oxo-5β-cholanoic acid benzyl ester (1352328-66-5) → benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate (1352328-67-6)

Guidance literature:

With sodium tetrahydroborate; cerium(III) chloride; In tetrahydrofuran; methanol; at 20 ℃; for 3h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jm201004p

Reference yield: 95.0%

benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate (1352328-67-6) → 3α,7α-dihydroxy-6α-ethyl-5β-cholanic acid benzyl ester

Guidance literature:

With sodium tetrahydroborate; cerium(III) chloride;

upstream raw materials:

3α-hydroxy-6-ethylidene-7-oxo-5β-cholanoic acid benzyl ester

Refernces