2-Iodopyridine-3-carboxylic acid

Base Information

Chemical Name:2-Iodopyridine-3-carboxylic acid
CAS No.:6042-35-9
Molecular Formula:C6H4INO2
Molecular Weight:249.008
Hs Code.:
DSSTox Substance ID:DTXSID20501640
Wikidata:Q82354130
Mol file:6042-35-9.mol

Synonyms:6042-35-9;2-Iodopyridine-3-carboxylic acid;2-Iodonicotinic acid;2-Iodo-nicotinic acid;2-Iodo nicotinic acid;iodonicotinic acid;2-Iodonicotinicacid;SCHEMBL2902900;DTXSID20501640;MFCD16556300;AKOS024261998;SB37892;BS-29080;CS-0212763;FT-0720374;EN300-124439;Z1269167145

Suppliers and Price of 2-Iodopyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Iodopyridine-3-carboxylic acid
10mg
$ 323.00

Crysdot
2-Iodonicotinicacid 95+%
1g
$ 402.00

Chemenu
2-iodonicotinicacid 95%
1g
$ 380.00

Alichem
2-Iodonicotinicacid
1g
$ 344.40

AK Scientific
2-Iodopyridine-3-carboxylicacid
10g
$ 3357.00

Total 15 raw suppliers

Chemical Property of 2-Iodopyridine-3-carboxylic acid

Chemical Property:

Melting Point:186-188 °C(Solv: acetone (67-64-1))
Boiling Point:350.0±27.0 °C(Predicted)
PKA:2.13±0.10(Predicted)
PSA：50.19000
Density:2.123±0.06 g/cm3(Predicted)
LogP:1.38440
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:248.92868
Heavy Atom Count:10
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

2-Iodopyridine-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)I)C(=O)O

Technology Process of 2-Iodopyridine-3-carboxylic acid

There total 1 articles about 2-Iodopyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6042-35-9
2-iodonicotinic acid

Guidance literature:: Hg-Salz III, KI;

Reference yield: 94.0%

: 6042-35-9
2-iodonicotinic acid

: 62-53-3
aniline

: 16344-24-4
2-(phenylamino)nicotinic acid

Guidance literature:: With copper(l) iodide; potassium carbonate; In N,N-dimethyl-formamide; for 8h;
DOI:10.1016/j.bmc.2020.115354

Reference yield:

: 6042-35-9
2-iodonicotinic acid

: 62-53-3
aniline

: N-methyl-N-(1-(2-(phenylamino)nicotinoyl)piperidin-4-yl)-2-trifluoromethyl-4-fluorobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; potassium carbonate / N,N-dimethyl-formamide / 8 h

2: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 8 h / 25 °C

With copper(l) iodide; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2020.115354