2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Base Information

Chemical Name:2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER
CAS No.:899362-89-1
Molecular Formula:C₁₃H₁₃ClN₂O₃S
Molecular Weight:312.777
Hs Code.:
Mol file:899362-89-1.mol

Synonyms:2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Suppliers and Price of 2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

There total 4 articles about 2-AMINO-4-(5-CHLORO-2-METHOXYPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: ethyl 2-bromo-3-(5-chloro-2-methoxyphenyl)-3-oxopropanoate

: 17356-08-0
thiourea

: 899362-89-1
ethyl 2-amino-4-(5-chloro-2-methoxyphenyl)thiazole-5-carboxylate

Guidance literature:: In ethanol; for 3h; Reflux;

Reference yield:

: 3438-16-2
5-chloro-2-methoxybenzoic acid

: 899362-89-1
ethyl 2-amino-4-(5-chloro-2-methoxyphenyl)thiazole-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1,1'-carbonyldiimidazole

1.2: Heating

2.1: bromine / 1,4-dioxane / 1 h

3.1: ethanol / 3 h / Reflux

With bromine; 1,1'-carbonyldiimidazole; In 1,4-dioxane; ethanol;

Reference yield:

: 6342-64-9
2-methoxy-5-chloroacetophenone

: 899362-89-1
ethyl 2-amino-4-(5-chloro-2-methoxyphenyl)thiazole-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C

1.2: 20 - 65 °C

2.1: bromine / 1,4-dioxane / 1 h

3.1: ethanol / 3 h / Reflux

With bromine; sodium hydride; In tetrahydrofuran; 1,4-dioxane; ethanol; mineral oil;