1-BENZYL-PIPERIDINE-4-BORONIC ACID

Base Information

Chemical Name:1-BENZYL-PIPERIDINE-4-BORONIC ACID
CAS No.:1251537-48-0
Molecular Formula:C12H18BNO2
Molecular Weight:219.091
Hs Code.:
Mol file:1251537-48-0.mol

Synonyms:1-BENZYL-PIPERIDINE-4-BORONIC ACID

Suppliers and Price of 1-BENZYL-PIPERIDINE-4-BORONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-Benzyl-piperidine-4-boronicacid 96%
500mg
$ 249.00

Crysdot
(1-Benzylpiperidin-4-yl)boronicacid 97%
1g
$ 972.00

American Custom Chemicals Corporation
1-BENZYL-PIPERIDINE-4-BORONIC ACID 95.00%
1G
$ 1130.85

American Custom Chemicals Corporation
1-BENZYL-PIPERIDINE-4-BORONIC ACID 95.00%
5MG
$ 500.31

Total 26 raw suppliers

Chemical Property of 1-BENZYL-PIPERIDINE-4-BORONIC ACID

Chemical Property:

PSA：43.70000
LogP:1.06330

Purity/Quality:

99%, ^*data from raw suppliers

1-Benzyl-piperidine-4-boronicacid 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-BENZYL-PIPERIDINE-4-BORONIC ACID

There total 4 articles about 1-BENZYL-PIPERIDINE-4-BORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 67848-71-9
4-chloro-1-benzylpiperidine

: 6562-41-0
chloro-bis(dimethylamino)borane

: 7732-18-5
water

: 1251537-48-0
N-benzylpiperidine-4-boronic acid

Guidance literature:: 4-chloro-1-benzylpiperidine; chloro-bis(dimethylamino)borane; With lithium; In tetrahydrofuran; at -5 - 5 ℃; for 1h; Inert atmosphere;

water; With hydrogenchloride; In tetrahydrofuran; at 0 - 20 ℃; pH=6;

Reference yield:

: N-benzyl-piperidin-4-boronic acid pinacol ester

: 7732-18-5
water

: 1251537-48-0
N-benzylpiperidine-4-boronic acid

Guidance literature:: N-benzyl-piperidin-4-boronic acid pinacol ester; water; With sodium periodate; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere; Sealed tube;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 18h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.0c00471

Reference yield:

: 4727-72-4
1-benzyl-4-hydroxypiperidine

: 1251537-48-0
N-benzylpiperidine-4-boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride; triethylamine / dichloromethane / 2 h / 20 - 40 °C

2.1: lithium / tetrahydrofuran / 1 h / -5 - 5 °C / Inert atmosphere

2.2: 0 - 20 °C / pH 6

With thionyl chloride; lithium; triethylamine; In tetrahydrofuran; dichloromethane;