2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde

Base Information

Chemical Name:2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde
CAS No.:1150100-46-1
Molecular Formula:C14H13NO4S
Molecular Weight:291.328
Hs Code.:
Mol file:1150100-46-1.mol

Synonyms:2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde;2-Methyl-6-[4-(methylsulfonyl)phenoxy]-3-pyridinecarboxaldehyde

Suppliers and Price of 2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde

Chemical Property:

Boiling Point:490.8±45.0 °C(Predicted)
PKA:0.85±0.22(Predicted)
PSA：81.71000
Density:1.306±0.06 g/cm3(Predicted)
LogP:3.47910

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde

There total 1 articles about 2-Methyl-6-(4-(Methylsulfonyl)phenoxy)nicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1150100-45-0
2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbonitrile

: 1150100-46-1
2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbaldehyde

Guidance literature:: 2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbonitrile; With diisobutylaluminium hydride; In dichloromethane; at -40 - -35 ℃; for 0.333333h;

With methanol; water; citric acid; In dichloromethane; at 20 ℃; for 6h;

With sodium hydrogencarbonate; In methanol; dichloromethane;

Reference yield: 65.0%

: 1150100-46-1
2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbaldehyde

: 1356537-58-0
C₂₁H₂₂F₂N₄O₂

: 1344151-78-5
C₃₅H₃₅F₂N₅O₅S

Guidance literature:: With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2011.08.096

Reference yield: 45.0%

: 1150100-44-9
2,4-difluoro-5-({[butyl(4-piperidinyl)amino]carbonyl}amino)benzamide

: 1150100-46-1
2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbaldehyde

: 949883-99-2
5-{[(butyl{1-[(2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinyl)methyl]-4-piperidinyl}amino)carbonyl]amino}-2,4-difluorobenzamide

Guidance literature:: 2,4-difluoro-5-({[butyl(4-piperidinyl)amino]carbonyl}amino)benzamide; 2-methyl-6-{[4-(methylsulfonyl)phenyl]oxy}-3-pyridinecarbaldehyde; In 1,2-dichloro-ethane; at 20 ℃; for 2h; Sonication;

With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; for 16h;

With water; sodium hydrogencarbonate; In dichloromethane; 1,2-dichloro-ethane;