Technology Process of methyl 4-{hydroxy[3-(quinolin-2-ylmethoxy)phenyl]amino}-4-oxobutanoate
There total 4 articles about methyl 4-{hydroxy[3-(quinolin-2-ylmethoxy)phenyl]amino}-4-oxobutanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
tetrahydrofuran;
for 1h;
Ambient temperature;
DOI:10.1021/jm00158a019
- Guidance literature:
-
Multi-step reaction with 3 steps
1: cesium carbonate, sodium carbonate, potassium iodide / acetone / 72 h / Heating
2: hydrazine hydrate / Pd/C (10percent) / tetrahydrofuran
3: 53 percent / triethylamine / tetrahydrofuran / 1 h / Ambient temperature
With
sodium carbonate; caesium carbonate; hydrazine hydrate; triethylamine; potassium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; acetone;
DOI:10.1021/jm00158a019
- Guidance literature:
-
Multi-step reaction with 3 steps
1: cesium carbonate, sodium carbonate, potassium iodide / acetone / 72 h / Heating
2: hydrazine hydrate / Pd/C (10percent) / tetrahydrofuran
3: 53 percent / triethylamine / tetrahydrofuran / 1 h / Ambient temperature
With
sodium carbonate; caesium carbonate; hydrazine hydrate; triethylamine; potassium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; acetone;
DOI:10.1021/jm00158a019
![N-[3-(Quinolin-2-ylmethoxy)-phenyl]-hydroxylamine](/Databaselist/images/loading.webp)
