2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-

Base Information

Chemical Name:2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-
CAS No.:742051-67-8
Molecular Formula:C₁₄H₁₈N₂O₂
Molecular Weight:246.309
Hs Code.:2934999090
Mol file:742051-67-8.mol

Synonyms:2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-

Suppliers and Price of 2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-(Piperidin-4-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95+%
1g
$ 673.00

Chemenu
6-(piperidin-4-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95%
1g
$ 636.00

American Custom Chemicals Corporation
6-(PIPERIDIN-4-YLMETHYL)-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE 95.00%
5MG
$ 500.01

Alichem
6-(Piperidin-4-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
1g
$ 751.80

Total 6 raw suppliers

Chemical Property of 2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-

Chemical Property:

Boiling Point:455.4±45.0 °C(Predicted)
PKA:12.73±0.20(Predicted)
PSA：53.85000
Density:1.166±0.06 g/cm3(Predicted)
LogP:1.97350
Storage Temp.:2-8°C

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

6-(Piperidin-4-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)-

There total 10 articles about 2H-1,4-Benzoxazin-3(4H)-one, 6-(4-piperidinylMethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1092366-86-3
benzyl 4-[4-(2-methoxy-2-oxoethoxy)-3-nitrobenzylidene]piperidine-1-carboxylate

: 742051-67-8
6-(4-piperidinylmethyl)-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 65 ℃; for 18h; under 2585.81 Torr;

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 742051-67-8
6-(4-piperidinylmethyl)-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: Multi-step reaction with 8 steps

1: magnesium

2: hydrogen bromide / water

3: hydrogen; platinum(IV) oxide; sulfuric acid / methanol

4: acetic acid; nitric acid

5: triethylamine / tetrahydrofuran; water

6: potassium carbonate / acetone / Heating

7: hydrogen; palladium on activated charcoal

8: hydrogenchloride / diethyl ether; isopropyl alcohol / Heating

With hydrogenchloride; platinum(IV) oxide; sulfuric acid; palladium on activated charcoal; hydrogen bromide; hydrogen; nitric acid; potassium carbonate; magnesium; acetic acid; triethylamine; In tetrahydrofuran; methanol; diethyl ether; water; isopropyl alcohol; acetone;
DOI:10.1021/op300185s

Reference yield:

: 35854-35-4
4-[(4-methoxyphenyl)methyl]pyridine

: 742051-67-8
6-(4-piperidinylmethyl)-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: Multi-step reaction with 7 steps

1: hydrogen bromide / water

2: hydrogen; platinum(IV) oxide; sulfuric acid / methanol

3: acetic acid; nitric acid

4: triethylamine / tetrahydrofuran; water

5: potassium carbonate / acetone / Heating

6: hydrogen; palladium on activated charcoal

7: hydrogenchloride / diethyl ether; isopropyl alcohol / Heating

With hydrogenchloride; platinum(IV) oxide; sulfuric acid; palladium on activated charcoal; hydrogen bromide; hydrogen; nitric acid; potassium carbonate; acetic acid; triethylamine; In tetrahydrofuran; methanol; diethyl ether; water; isopropyl alcohol; acetone;
DOI:10.1021/op300185s