4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE

Base Information

• Chemical Name: 4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE
• CAS No.: 81430-75-3
• Molecular Formula: C₈H₄F₄N₂
• Molecular Weight: 204.127
• Mol file: 81430-75-3.mol

Synonyms:4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE;4,5,6,7-Tetrafluoro-2-methyl-1H-benzo[d]imidazole

Chemical Property of 4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE

Chemical Property:

• PSA: 28.68000
• LogP: 2.42770

Purity/Quality:

98% ^*data from raw suppliers

4,5,6,7-tetrafluoro-2-methyl-1H-Benzimidazole 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE

There total 3 articles about 4,5,6,7-TETRAFLUORO-2-METHYL-1H-1,3-BENZODIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,4,5,6-tetrafluoro-benzene-1,2-diamine (2993-07-9) + acetic anhydride (108-24-7) → 2-methyl-4,5,6,7-tetrafluorobenzimidazole (81430-75-3)

Guidance literature:

With hydrogenchloride; for 18h; Heating;

DOI:10.1007/BF00507000

Reference yield: 40.0%

3,4,5,6-tetrafluoro-N,N'-bis(diacetyl)-o-phenylendiamine (81430-63-9) → 2-methyl-4,5,6,7-tetrafluorobenzimidazole (81430-75-3)

Guidance literature:

With hydrogenchloride; ammonia; Heating;

DOI:10.1007/BF00507000

Reference yield:

3,4,5,6-tetrafluoro-benzene-1,2-diamine (2993-07-9) → 2-methyl-4,5,6,7-tetrafluorobenzimidazole (81430-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / HCl 36percent / 3 h / Heating

2: 40 percent / 1) 10percent HCl; 2) NH₃ gas / Heating

With hydrogenchloride; ammonia;

DOI:10.1007/BF00507000

upstream raw materials:

3,4,5,6-tetrafluoro-benzene-1,2-diamine

acetic anhydride

3,4,5,6-tetrafluoro-N,N'-bis(diacetyl)-o-phenylendiamine

Downstream raw materials:

1-ethyl-2-methyl-3,3,3-trifluoropropyl-4,5,6,7-tetrafluorobenzimidazolium p-toluenesulfonate

1,3-diethyl-2-methyl-4,5,6,7-tetrafluorobenzimidazolium p-toluenesulfonate

Refernces