tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

Base Information

Chemical Name:tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
CAS No.:1149333-40-3
Molecular Formula:C13H19N3O2
Molecular Weight:249.313
Hs Code.:
Mol file:1149333-40-3.mol

Synonyms:1,1-Dimethylethyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5h)-carboxylate;tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate;1,6-Naphthyridine-6(5H)-carboxylic acid, 2-amino-7,8-dihydro-, 1,1-dimethylethyl ester

Suppliers and Price of tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

Chemical Property:

PSA：68.45000
LogP:2.47610

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

There total 11 articles about tert-butyl 2-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

: 1346673-94-6
tert-butyl 2-[(diphenylmethylidene)amino]-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate

: 1149333-40-3
2-amino-7,8-dihydro-1,6-naphthyridin-6(5H)-carboxylic acid tert-butyl ester

Guidance literature:: With hydroxylamine hydrochloride; In methanol; at 20 ℃; for 3.5h; Cooling with ice;

Reference yield: 48.0%

: 1149333-39-0
tert-butyl 2-(trifluoromethanesulfonyloxy)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate

: 1149333-40-3
2-amino-7,8-dihydro-1,6-naphthyridin-6(5H)-carboxylic acid tert-butyl ester

Guidance literature:: With Benzophenone imine; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; for 10h; Inert atmosphere; Reflux;

Reference yield: 46.0%

: 1013-88-3
Benzophenone imine

: 1149333-39-0
tert-butyl 2-(trifluoromethanesulfonyloxy)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate

: 1149333-40-3
2-amino-7,8-dihydro-1,6-naphthyridin-6(5H)-carboxylic acid tert-butyl ester

Guidance literature:: Benzophenone imine; tert-butyl 2-(trifluoromethanesulfonyloxy)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate; With caesium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; Heating / reflux;

With hydroxylamine hydrochloride; sodium acetate; In methanol; at 20 ℃; for 5h;