Termitomycamide E

Base Information

• Chemical Name: Termitomycamide E
• CAS No.: 1177258-62-6
• Molecular Formula: C26H41NO2
• Molecular Weight: 399.617
• Mol file: 1177258-62-6.mol

Synonyms:Termitomycamide E

Chemical Property of Termitomycamide E

Chemical Property:

• PSA: 49.33000
• LogP: 7.25530

Purity/Quality:

99% ^*data from raw suppliers

Termitomycamide E ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Termitomycamide E

There total 1 articles about Termitomycamide E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

tyrosamine (51-67-2) + linoleic acid (60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3) → termitomycamide E (1177258-62-6)

Guidance literature:

linoleic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

tyrosamine; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jm900324e

Reference yield:

[11C]methyl iodide (54245-42-0) + termitomycamide E (1177258-62-6) → C26(11)CH43NO2

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In water; N,N-dimethyl-formamide; at 55 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/jm900324e

upstream raw materials:

tyrosamine

linoleic acid

Refernces

• 1、 Wyffels, Leonie,Muccioli, Giulio G.,De Bruyne, Sylvie,Moerman, Lieselotte,Sambre, Johan,Lambert, Didier M.,De Vos, Filip. "Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain". experimental part. p. 4613 - 4622. Retrieved 2010/02/28.