N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide

Base Information

Chemical Name:N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide
CAS No.:1234708-04-3
Molecular Formula:C22H20N6O3
Molecular Weight:416.439
Hs Code.:
Mol file:1234708-04-3.mol

Synonyms:N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide;2-(pyridin-2-yl)pyriMidine-5-carboxylic acid 3-[5-(1-hydroxy-1-Methylethyl)-1,2,4]oxadiazol-3-yl-benzylaMide;SAR191801;tert-butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane SAR191801;hPGDS-IN-1;SAR191801,2-Pyridin-2-yl-pyrimidine-5-carboxylic acid 3-[5-(1-hydroxy-1-methyl-ethyl)-[1,2,4]oxadiazol-3-yl]-benzylamide;N-[[3-[5-(1-Hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide

Suppliers and Price of N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SAR191801
5mg
$ 220.00

TRC
SAR191801
25mg
$ 605.00

DC Chemicals
hPGDS-IN-1 >98%
250 mg
$ 950.00

DC Chemicals
hPGDS-IN-1 >98%
100 mg
$ 550.00

Crysdot
hPGDS-IN-1 98+%
50mg
$ 1050.00

Crysdot
hPGDS-IN-1 98+%
5mg
$ 210.00

Crysdot
hPGDS-IN-1 98+%
10mg
$ 315.00

ChemScene
hPGDS-IN-1 99.82%
50mg
$ 1500.00

ChemScene
hPGDS-IN-1 99.82%
5mg
$ 300.00

ChemScene
hPGDS-IN-1 99.82%
10mg
$ 450.00

Total 14 raw suppliers

Chemical Property of N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide

Chemical Property:

PSA：126.92000
LogP:3.13690

Purity/Quality:

99%, ^*data from raw suppliers

SAR191801 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses SAR191801 is a novel hematopoietic prostaglandin D synthase (hPGDS) inhibitor.

Technology Process of N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide

There total 13 articles about N-(3-(5-(2-hydroxypropan-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)-2-(pyridin-2-yl)pyriMidine-5-carboxaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1068976-90-8
methyl 2-(pyridin-2-yl)pyrimidine-5-carboxylate

: 1286182-70-4
3-[5-(1-hydroxy-1-methyl-ethyl)-[1,2,4]oxadiazol-3-yl]benzyl-amine

: 1234708-04-3
2-(pyridin-2-yl)pyrimidine-5-carboxylic acid 3-[5-(1-hydroxy-1-methylethyl)-1,2,4]oxadiazol-3-yl-benzylamide

Guidance literature:: With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; In 2-methyltetrahydrofuran; for 3h; Inert atmosphere; Heating;

Reference yield: 79.0%

: 1286182-70-4
3-[5-(1-hydroxy-1-methyl-ethyl)-[1,2,4]oxadiazol-3-yl]benzyl-amine

: 2-pyridin-2-yl-pyrimidine-5-carbonyl chloride hydrochloride

: 1234708-04-3
2-(pyridin-2-yl)pyrimidine-5-carboxylic acid 3-[5-(1-hydroxy-1-methylethyl)-1,2,4]oxadiazol-3-yl-benzylamide

Guidance literature:: With triethylamine; In 1-methyl-pyrrolidin-2-one; for 2.5h;

Reference yield: 42.0%

: 1286182-69-1
3-[5-(1-hydroxy-1-methyl-ethyl)-[1,2,4]oxadiazol-3-yl]benzyl-amine hydrochloride

: 933988-22-8
2-(pyridin-2-yl)pyrimidine-5-carboxylic acid

: 1234708-04-3
2-(pyridin-2-yl)pyrimidine-5-carboxylic acid 3-[5-(1-hydroxy-1-methylethyl)-1,2,4]oxadiazol-3-yl-benzylamide

Guidance literature:: 3-[5-(1-hydroxy-1-methyl-ethyl)-[1,2,4]oxadiazol-3-yl]benzyl-amine hydrochloride; 2-(pyridin-2-yl)pyrimidine-5-carboxylic acid; With 4-methyl-morpholine; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In N,N-dimethyl-formamide; at 20 ℃; for 3h;