1(2H)-Naphthalenone, 3,4-dihydro-6-octyl-

Base Information

• Chemical Name: 1(2H)-Naphthalenone, 3,4-dihydro-6-octyl-
• CAS No.: 945632-75-7
• Molecular Formula: C₁₈H₂₆O
• Molecular Weight: 258.404
• Hs Code.: 2914399090
• Mol file: 945632-75-7.mol

Synonyms:6-octyl-3,4-dihydro-2H-naphthalen-1-one;1(2H)-Naphthalenone, 3,4-dihydro-6-octyl-

Chemical Property of 1(2H)-Naphthalenone, 3,4-dihydro-6-octyl-

Chemical Property:

• PSA: 17.07000
• LogP: 5.10860
• Storage Temp.: 2-8°C

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

6-Octyl-3,4-dihydronaphthalen-1(2H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1(2H)-Naphthalenone, 3,4-dihydro-6-octyl-

There total 4 articles about 1(2H)-Naphthalenone, 3,4-dihydro-6-octyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate (144464-64-2) → 6-octyl-3,4-dihydro-2H-naphthalen-1-one (945632-75-7)

Guidance literature:

oct-1-ene; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 20 ℃;

5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate; With potassium phosphate; potassium bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; at 65 ℃; for 2h;

Reference yield: 56.0%

oct-1-ene (111-66-0,25068-25-1) + 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate (144464-64-2) → 6-octyl-3,4-dihydro-2H-naphthalen-1-one (945632-75-7)

Guidance literature:

oct-1-ene; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 20 ℃;

5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate; With potassium phosphate; water; potassium bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 65 ℃; for 2 - 3h; Product distribution / selectivity;

Reference yield:

9-octyl-9-bora-bicyclo[3.3.1]nonane (30089-00-0) + 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate (144464-64-2) → 6-octyl-3,4-dihydro-2H-naphthalen-1-one (945632-75-7)

Guidance literature:

With dipotassium hydrogenphosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium bromide; In tetrahydrofuran; water; for 3h; Reflux;

DOI:10.1016/j.bmcl.2010.02.006

upstream raw materials:

5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate

oct-1-ene

9-octyl-9-bora-bicyclo[3.3.1]nonane

6-Hydroxy-1-tetralone

Downstream raw materials:

2-bromo-6-octyl-3,4-dihydro-2H-naphthalen-1-one

2-acetylamino-2-(6-octyl-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-malonic acid diethyl ester

2-acetylamino-2-(6-octyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-malonic acid diethyl ester

N-[2-hydroxy-1-hydroxymethyl-1-(6-octyl-1,2,3,4-tetrahydro-naphthalen-2-yl)ethyl]-acetamide