4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL

Base Information

• Chemical Name: 4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL
• CAS No.: 116831-33-5
• Molecular Formula: C₁₅H₁₄BrF
• Molecular Weight: 293.179
• Mol file: 116831-33-5.mol

Synonyms:4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL;4-Bromo-2-fluoro-4'-propyl-1,1'-biphenyl

Chemical Property of 4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL

Chemical Property:

• Boiling Point: 340.8±30.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.306±0.06 g/cm3(Predicted)
• LogP: 5.20770

Purity/Quality:

99%min ^*data from raw suppliers

4-BROMO-2-FLUORO-4'-PROPYL-BIPHENYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL

There total 3 articles about 4-BROMO-2-FLUORO-4'-PROPYLBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-fluoro-4-bromo-4'-propionylbiphenyl (116831-22-2) → 4'-propyl-2-fluoro-4-bromobiphenyl (116831-33-5)

Guidance literature:

With triethylsilane; In trifluoroacetic acid; for 2.5h; Ambient temperature;

Reference yield:

1-bromo-3-fluoro-4-phenylbenzene (41604-19-7) → 4'-propyl-2-fluoro-4-bromobiphenyl (116831-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / anhydrous aluminium chloride / various solvent(s) / 16 h / Ambient temperature

2: 81 percent / triethylsilane / trifluoroacetic acid / 2.5 h / Ambient temperature

With triethylsilane; aluminium trichloride; In trifluoroacetic acid;

Reference yield:

→ 4'-propyl-2-fluoro-4-bromobiphenyl (116831-33-5)

Guidance literature:

upstream raw materials:

2-fluoro-4-bromo-4'-propionylbiphenyl

1-bromo-3-fluoro-4-phenylbenzene

Downstream raw materials:

4-propyl-2,4,3'-trifluoro-[1,1 '; 4', 1]terphenyl

2'-fluoro-4-n-propyl-p-terphenyl

Refernces

• 1、 -. "Fluorinated 4"-cyano substituted terphenyls". . . Retrieved 2008/06/13.
• 2、 Chan, L. K. M.,Gray, G. W.,Lacey, D.. "Synthesis and Evaluation of Some 4,4''-Disubstituted Lateral Fluoro-1,1':4',1''-terphenyls". . p. 185 - 204. Retrieved 2007/10/02.