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Technology Process of Benzamil hydrochloride

Benzamil hydrochloride

Base Information
  • Chemical Name:Benzamil hydrochloride
  • CAS No.:161804-20-2
  • Molecular Formula:C13H14ClN7OHCl
  • Molecular Weight:0
  • Hs Code.:2924299090
  • European Community (EC) Number:634-062-0
  • UNII:I7L324A070
  • DSSTox Substance ID:DTXSID601017145
  • Wikidata:Q27280550
  • ChEMBL ID:CHEMBL1256878
  • Mol file:161804-20-2.mol
Benzamil hydrochloride

Synonyms:Benzamil hydrochloride;161804-20-2;Benzamil HCl;Benzamil (hydrochloride);Benzylamiloride hydrochloride;Benzamil*HCl;Benzylamiloride (hydrochloride);N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride;3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride;I7L324A070;C13H14ClN7O;3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide;hydrochloride;C13-H14-Cl-N7-O;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-(imino((phenylmethyl)amino)methyl)-, hydrochloride (1:1);3,5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide, monohydrochloride;SMR000326882;SR-01000075711;Prestwick_985;MLS000860024;MLS002153339;MLS002153937;SPECTRUM2300179;SCHEMBL9464171;CHEMBL1256878;UNII-I7L324A070;HY-B1546A;DTXSID601017145;HMS1570C15;BCP20263;EX-A1706;Tox21_500211;AKOS024457593;CCG-220657;CCG-221515;CS-7692;LP00211;NCGC00093683-01;NCGC00093683-02;NCGC00093683-03;NCGC00093683-04;NCGC00178271-01;NCGC00178271-02;NCGC00260896-01;AC-33607;MS-25569;B-160;EU-0100211;B 2417;J-009861;J-017341;SR-01000075711-1;SR-01000075711-4;Q27280550;hydrochloride.;3,5-DIAMINO-N-(N-BENZYLCARBAMIMIDOYL)-6-CHLOROPYRAZINE-2-CARBOXAMIDE HCL;(E)-3,5-diamino-N-(amino(benzylamino)methylene)-6-chloropyrazine-2-carboxamide hydrochloride

Suppliers and Price of Benzamil hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • BenzamilHydrochloride
  • 10mg
  • $ 85.00
  • Sigma-Aldrich
  • Benzamil hydrochloride hydrate ≥98% (HPLC)
  • 10mg
  • $ 86.50
  • Sigma-Aldrich
  • Benzamil hydrochloride hydrate ≥98% (HPLC)
  • 50mg
  • $ 311.00
  • DC Chemicals
  • Benzamil(hydrochloride) >98%
  • 250 mg
  • $ 800.00
  • CSNpharm
  • BenzamilHCl
  • 50mg
  • $ 255.00
  • CSNpharm
  • BenzamilHCl
  • 100mg
  • $ 435.00
  • Crysdot
  • 3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamidehydrochloride 97%
  • 250mg
  • $ 980.00
  • ChemScene
  • Benzamilhydrochloride 99.60%
  • 50mg
  • $ 312.00
  • ChemScene
  • Benzamilhydrochloride 99.60%
  • 100mg
  • $ 552.00
  • ChemScene
  • Benzamilhydrochloride 99.60%
  • 5mg
  • $ 60.00
Total 11 raw suppliers
Chemical Property of Benzamil hydrochloride
Chemical Property:
  • PSA：142.80000 
  • LogP:3.59470 
  • Storage Temp.:2-8°C 
  • Solubility.:methanol: soluble10mg/mL 
  • Hydrogen Bond Donor Count:5
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:4
  • Exact Mass:355.0715135
  • Heavy Atom Count:23
  • Complexity:413
Purity/Quality:

97% *data from raw suppliers

BenzamilHydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): Xi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N.Cl
  • Description Benzamil (161804-21-2) is a more potent (Ki = 10 nM vs 182 nM1, IC50 = 9 μM2) version of the epithelial sodium channel blocker Amiloride. It is also an inhibitor of Na+/Ca2+ exchange transport (IC50 = 11 μM)2 and the Na+/H+ antiporter (IC50 = 80 nM)2.
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